A •
Alfred Jefferson Vaughan Jr. (1830–1899), American civil engineer, planter, soldier and writer •
Alden Vaughan (born 1929), American historian •
Anne Vaughan, Countess of Carbery (1663–1689/90) •
Arky Vaughan (1912–1952), American professional baseball player •
Arthur Owen Vaughan (1863–1919), English-born writer, soldier and Welsh nationalist
B •
Ben Vaughan (born 1999), English boxer •
Benjamin Vaughan (1751–1835), British politician •
Benjamin Vaughan (bishop) (1917–2003), Bishop of Swansea and Brecon in the Church in Wales •
Benji Vaughan, British psychedelic trance and psybient musician •
Bernard Vaughan (1847–1922), English Roman Catholic clergyman •
Bernard Vaughan (actor) (early 20th century), British silent film actor •
Beryl Vaughan (1919–2016), American actress •
Bob Vaughan (born 1945), British mathematician •
Brian K. Vaughan (born 1976), American comic book and television writer •
Bruce Vaughan (born 1956), American professional golfer •
Byrde M. Vaughan (1862–1941), American lawyer and politician
C •
Charles John Vaughan (1816–1897), English scholar and churchman •
Clyde Vaughan, American basketball coach and player •
Colin Vaughan (1931–2000), Canadian television journalist, architect, urban activist and politician •
Crawford Vaughan (1874–1947), Australian politician, Premier of South Australia 1915–1917
D •
Daniel Vaughan (1897–1975), Irish politician and farmer •
David Vaughan (disambiguation), several people •
Denis Vaughan (1926–2017), Australian-born orchestral conductor and multi-instrumentalist • Diana Vaughan, fictitious character in the 1890s
Taxil hoax •
Don Vaughan (ice hockey) (born 1961), Canadian ice-hockey coach and former player •
Don Vaughan (landscape architect) (born 1937), American landscape architect •
Dorothy Vaughan (1910–2008), African American mathematician •
Dustin Vaughan (born 1991), American football player
E •
Edwin Campion Vaughan (1897–1931), British Army officer and diarist •
Louisa Elizabeth Rolls Vaughan (1810–1853), Welsh Catholic laywoman and mother
F •
Frankie Vaughan (1928–1999), British singer
G •
Genevieve Vaughan (born 1939), American expatriate semiotician, peace activist, feminist, and philanthropist •
Gerard Vaughan (British politician) (1923–2003), British psychiatrist and politician •
George Augustus Vaughn Jr. (1897–1989), American fighter ace •
Greg Vaughan (born 1973), American actor
H •
Hal Vaughan (1928–2013), American author based in France •
Harp Vaughan (1903–1978), American football player •
Harry Vaughan (disambiguation), several people •
Hayley Vaughan, fictional character from American TV series
All My Children •
Henry Vaughan (disambiguation), several people •
Herbert Vaughan (1832–1903), English cardinal •
Herbert Millingchamp Vaughan (1870–1948), Welsh author and historian •
Horace Worth Vaughan (1867–1922), American lawyer, jurist, and politician •
Howard Vaughan (John Howard Vaughan, 1879–1955), Australian politician
I •
Ivan Vaughan (1942–1993), British musician, teacher and author, introduced John Lennon to Paul McCartney
J •
James Vaughan (disambiguation), several people • Dame
Janet Vaughan (1899–1993), British physiologist, Principal of Somerville College, Oxford •
Jimmie Vaughan (born 1951), American guitarist and singer •
John Vaughan (disambiguation), several people •
Johnny Vaughan (born 1966), English broadcaster and journalist •
Jonathan Vaughn (born 1981), British-American organist and choir director •
Jon the Dentist (born 1965), British music record producer •
Josh Vaughan (born 1986), American football player •
Joshua Vaughan (born 2006), English actor •
Justin Vaughan (born 1967), English-New Zealand doctor and cricket executive
K •
Kaye Vaughan (1931–2023), Canadian football player •
Keith Vaughan (1912–1977), British painter •
Kenny Vaughan, American guitarist •
Kit Vaughan (born 1953), South African professor of biomedical engineering
M •
Malcolm Vaughan (1929–2010), Welsh traditional pop music singer and actor •
Mark Vaughan (born 1985), Irish Gaelic footballer •
Martin Vaughan (1931–2022), Australian actor •
Megan Vaughan, British historian •
Michael Vaughan (born 1974), English cricketer •
Mike Vaughan (born 1954), American football player with Oklahoma Sooners •
Murray Vaughan (1899–1986), Canadian philanthropist
N •
Nigel Vaughan (born 1959), Welsh professional footballer •
Norman D. Vaughan (1905–2005), American dogsled driver and explorer •
Norman Vaughan (comedian) (1927–2002), English comedian
P •
Paul Vaughan (1925–2014), British journalist and radio and TV presenter •
P. W. Vaughan (1871–1945), Australian bank manager •
Peter Vaughan (disambiguation), several people •
Philip Vaughan (18th century), Welsh inventor of the ball bearing •
Pinkerton R. Vaughn (1839–1866), American Medal of honor recipient
Q •
Quincy Vaughn (born 2001), Canadian football player
R •
Ralph Vaughan Williams (1872–1958), English composer •
Rhydian Vaughan (born 1988), Taiwanese-British actor •
Rice Vaughan (died c. 1672), Anglo-Welsh lawyer and economist •
Richard Vaughan (disambiguation), several people •
R. M. Vaughan (born 1965), Canadian poet, novelist and playwright •
Robert Vaughan (disambiguation), several people •
Roger Vaughan (disambiguation), several people •
Rowland Vaughan (disambiguation), several people
S •
Sarah Vaughan (1924–1990), American jazz singer •
Sarah Vaughan (writer) (born 1972), British journalist and writer •
Scipio Vaughan (c.1784–1840), American artisan •
Scooter Vaughan (born 1989), American ice hockey player •
Stephen Vaughan (disambiguation), several people •
Stevie Ray Vaughan (1954–1990), American guitarist, singer-songwriter and record producer •
Stoll Vaughan, American singer-songwriter
T •
Terri Vaughan (born 1956), American economist •
Thomas Vaughan (disambiguation), several people •
Tom Vaughan (disambiguation), several people •
Tony Vaughan (footballer) (born 1975), English footballer • Sir
Tudor Vaughan (1870–1929), British diplomat
V •
Vernon H. Vaughan (1838–1878), American politician •
Victor C. Vaughan (1851–1929), American physician, medical researcher, and AMA President
W •
William Vaughan (disambiguation), multiple people ==Notable people with the surname Vaughn==