On 30 April 2008, Wan Azizah became the first woman to hold the post of
Leader of the Opposition. Her position was acknowledged during coalition negotiations by the
Malaysian United Indigenous Party, led by
Mahathir Mohamad and
Muhyiddin Yassin. This recognition helped sustain the PKR's leadership role within the opposition despite internal divisions and uncertainty over succession. That same year, Wan Azizah sent a letter to
Myanmar's ambassador expressing concern over the
military junta's decision to proceed with a
constitutional referendum despite the ongoing
Cyclone Nargis crisis. She submitted a motion urging
Speaker Pandikar Amin Mulia to call for a postponement of the vote, to prioritise relief efforts and to press the regime to grant greater access to aid workers. She also called on the
Malaysian government to use its influence to advocate for a delay, though the motion was rejected on the grounds of Malaysia's policy of neutrality and noninterference. Her tenure as opposition leader ended on 28 August 2008, when she resigned to make way for her husband, who succeeded her. In 2010, Wan Azizah Wan Ismail called for the abolition of
Malay supremacy, highlighting its exploitation by a small elite and advocating for Malaysian children to grow up as "Malay of Integrity." In June 2011, she faced a
RM200 million defamation suit filed by
Federal Land Development Authority (Felda) over articles in '''', with the
High Court deciding her case would be heard separately from a related suit against former
deputy minister Tan Kee Kwong. In April 2012, she urged Felda to return of
Sabah land, arguing the agency had failed to develop it for settlers and had converted it into profitable
palm oil plantations. In 2013, she confirmed she would not contest the
general election, focusing instead on the PKR's campaign and engaging women voters. In 2014, the High Court ruled in favour of Felda, raising the defamation damages Wan Azizah and her co-defendants were required to pay from RM70,000 to RM2 million. Later that year, on 9 March, the PKR selected Wan Azizah as its candidate for the
Kajang by-election, and she won the seat on 23 March with a majority of 5,379 votes. In August, she received support from the
Pan-Malaysian Islamic Party to lead
Selangor, a move by the opposition to challenge the long-ruling
UMNO-led
Barisan Nasional (BN) coalition, which had faced criticism over governance and ethnic policies. Wan Azizah later contested the Permatang Pauh seat for the PKR, winning with a majority of 8,841 votes, and was sworn in as opposition leader on 18 May 2015, reclaiming the seat vacated by Anwar following his imprisonment in February. In 2016, she helped forge an alliance between the opposition coalition and Mahathir's
Malaysian United Indigenous Party. By January 2018, the coalition, known as the
Alliance of Hope, designated Mahathir as its prime ministerial candidate and Wan Azizah as his prospective deputy, uniting diverse factions and contributing to BN's defeat in the 2018 general election. Wan Azizah subsequently contested and won the
Pandan seat with a majority of 52,543 votes. == Deputy Prime Minister ==