Andrew "Andy" Larkin Andy is a teenager who loves to prank and joke people as well as annoy his friends and family (especially his sister), but often gets into trouble. His best friend is Danny and he has a crush on Lori. His catchphrase is "Cheque, please!" His name comes from
Andy Griffiths, whom he is based on.
Daniel "Danny" Tadeus Pickett Andy's best friend and right-hand man, helping him out with countless pranks and jokes. His last name has always been
Pickett. The name "Danny Pickett" is taken directly from the Just books. It's revealed in The Unfortunate One, that Danny is an Aries.
Lori Mackney Andy's crush but she is dismayed by his childishness due to his pranking. It is hinted that she returns Andy's feelings and dislikes Jen because she thinks that Jen abuses Andy. She wears a cropped green tank top, blue skirt and slide sandals. She is based on Lisa Mackney from the Just books.
The Larkin family •
Mr. Al Larkin: Andy and Jen's father and Freida's husband who also used to be a prankster, known as "The Mystery Prankster and Jester", aka "The Mystery Prankster and Jester of East Gackle" (he hides this fact from his family). However, he was cured of pranking and joking by
school counselor, Mrs. Murphy. •
Mrs. Freida Larkin: Andy and Jen's mother and Al's wife. She knows nothing about her husband's past as a prankster and jester. •
Jennifer "Jen" Larkin: Andy's older sister who is always cranky and irritable. She blames her younger brother Andy for almost everything and finds his practical jokes childish and unfunny. She is unaware of her father's past as a prankster and jester. •
Spank Larkin: Andy's fat and lazy dog. Spank frequently yawns, especially after going for a walk. He also appears to have
flatulence problems. •
Norman Larkin: Andy's grandfather and Al's father who is also a prankster and jester, implying that the male side of the Larkin family comes from a long line of pranksters and jesters (apparently with the exception of Al, but in the episode "Mind Games" it was revealed that he also used to be a prankster and jester, possibly even greater than his son or father).
Recurring/minor characters •
Teri: Jen's best friend. •
Jervis Coltrane: A Canadian French snob who has a crush on Lori Mackney and dreams of being the Prime Minister of Canada. •
Peter Lik and Andrew Leech: Peter and Andrew are Andy's and Danny's nemeses. They are usually referred to as Lik and Leech. •
Craig Bennett: Jen's crush and one of the best athletes of East Gackle. •
Martin Bonwick: He is a stereotypically nervous nerd who very often gets bullied. •
Victor "Vic" Muskowitz (Mush): The pizza delivery man of East Gackle who is a good friend of Andy and Danny and he sometimes helps them with pranks. •
Steve Rowgee Jr.: A dumb police officer who is the incompetent son of Steve Rowgee Sr. •
Steve Rowgee Sr.: A police officer who is an old man, who always commands Steve Rowgee Jr. (his son) and is nicknamed the Iron Fisted Maniac. •
Principal DeRosa: He is the bad-tempered principal of the school in East Gackle who is obsessed with punishing Andy. •
Mr. Hutchins: One of the many teachers at East Gackle school, Andy likes to prank and joke him more than the other teachers. •
Mayor Henry K. Roth: The mayor of East Gackle. •
Mayor Simms: Mayor of West Gackle and Mayor Henry K. Roth's rival. •
Clyde: The janitor of the school. •
Hazel Strinner: She has a crush on Andy and Lori's protecting friend. •
Louella Berman: Frieda's best friend. •
Mrs. Wibbles: Principal DeRosa's secretary. ==Voice actors==