1st round The first round was held on April 12, 2025, in
Muscat,
Oman. The talks were led by US Special Envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi; each delegation was in separate rooms, with messages relayed through Omani mediators. Moreover, Iran had reportedly proposed steps to deescalate tensions, including a pledge to disarm and freeze the activities of
Hamas, the
Houthis,
Hezbollah, and
Hashd al-Shaabi. US envoy Witkoff reportedly welcomed the proposals presented by the Iranian delegation in Muscat, which were unexpected by the Iranian side. Later that month, IAEA chief
Rafael Grossi visited Iran and met Araghchi. Grossi said they were "in a very crucial stage of these important negotiations" and that he worked to facilitate the process.
2nd round The second round of Omani-mediated talks in
Rome occurred on April 19, 2025, one week after the initial meeting in Muscat, the capital of Oman in four hours. Once again, the indirect discussions were led by Araghchi and Witkoff, with messages conveyed through Omani Foreign Minister Badr al-Busaidi. Afterwards, US president Trump said that he was open to meeting Iran's Supreme Leader Ali Khamenei. Following the second round of talks, the Israeli Air Force reportedly conducted drills simulating an Iranian missile attack on Israeli airbases. Meanwhile, Iran was reported to be constructing a large security barrier around two underground tunnel complexes linked to its main nuclear facility. Russia promised to fund the construction of a nuclear reactor in Iran. China, Russia, and Iran held a joint meeting with the International Atomic Energy Agency (IAEA) on April 24 to discuss Iran's nuclear program.
3rd round The third round of high-level negotiations took place on April 26, 2025, along with the first round of expert-level talks. The high-level talks were described as serious and productive, with both sides aiming for an agreement based on mutual respect. Araghchi reported progress but noted that key differences remained. however, Iranian foreign minister Araghchi later warned the European parties against initiating snapback sanctions, cautioning that such a move would severely harm the negotiations — a warning he repeated several times in the following weeks. Iran proposed holding further talks with European participation, while also offering investment opportunities. On April 30, the US Treasury sanctioned 6 Chinese chemical components companies connected to Iran. On May 1, defense secretary
Hegseth posted that Iran will pay for supporting Houthis attacks on merchant ships in Red Sea crisis. President Trump warned of secondary sanctions on entities buying any oil or petrochemicals from Iran. Rubio warned to walk away from nuclear enrichment. Araghchi canceled the May 4 meeting citing a "technical reason". Trump has called for the full dismantling of nuclear enrichment. Iran then unveiled a new ballistic missile and threatened to hit US military bases.
Revolutionary Guard General
Salami warned that IRGC would open hell gates on invaders. The fourth round of negotiations, originally scheduled for May 3, 2025, in Rome, was postponed amid rising tensions. Iranian officials cited US sanctions, military action against the Houthis, and what they described as "contradictory behaviour and provocative statements" by Washington as contributing factors, while stating that a new date would depend on the US approach. Oman, which mediated previous rounds, referred to logistical reasons for the delay. A source familiar with the matter indicated that the United States had not confirmed its participation, and that the timing and venue for the next round remained unconfirmed. The negotiations were taking place amid daily
rolling blackouts across Iran due to
ongoing electricity shortages. Supporters of Iran's nuclear program argue that the country requires nuclear energy for electricity generation. The proposed change was opposed by Iranians across the political spectrum, who displayed rare unity in rejecting the possible American move. Later that day, however, Trump told reporters that he had yet to make a decision whether to use "Arabian Gulf", stating, "I don't want to hurt anybody's feelings", appearing to acknowledge Iran's fierce opposition to that name. He said he would decide while on his visit, yet no announcement was made.
JD Vance said that the deal would allow
Iran to rejoin the global economy. Republican Senators
Lindsey Graham and
Tom Cotton warned the next day that any future US–Iran nuclear agreement would require
Senate approval to be durable, and that such approval would only be possible if Iran fully dismantled its enrichment capabilities and addressed its missile and terrorism activities. A group of Senate Republicans called for the inclusion of a
123 Agreement, which would impose strict safeguards and require full dismantlement before any cooperation. While such agreements regulate peaceful nuclear cooperation, experts noted that applying one to Iran would be highly unusual due to its history of proliferation violations and ongoing
IAEA investigations. The video allegedly revealed a previously unknown Iranian nuclear weapons site, a 2,500-acre facility referred to as the "Rainbow Site", in the
Semnan province. According to Fox News, it has operated for over a decade under the cover of the chemical company "Diba Energy Siba", and is involved in
tritium extraction, a process with almost no civilian or commercial uses, but known to enhance nuclear weapons. Araghchi rejected the report, calling it Israeli-driven propaganda aimed at disrupting the negotiations with the US He added that Iran must permanently end its enrichment program, stressing that this requires dismantling its facilities at
Natanz,
Fordow, and
Isfahan, and ensuring there is no weaponization. During his speech on May 10, Khamenei supported chants of "death to America".
4th round The fourth round of talks were held on May 11 in Oman prior to Trump's visit to the Middle East. The talks were high-level only, focusing on a broader framework, with technical negotiators not participating. According to unnamed Iranian officials, Iran proposed a joint nuclear-enrichment project with regional Arab states and US investment as an alternative to dismantling its nuclear program. US envoy Steve Witkoff denied this was being discussed. The plan's feasibility remained uncertain given regional tensions and the lack of diplomatic ties between Iran and the US for 45 years. On May 12, the US imposed new sanctions targeting Iranian nuclear research with possible military applications, followed days later by sanctions on individuals and entities in China and Iran over support for Iran's ballistic missile program. On May 14, 52 senators and 177 congressmen wrote a letter to Trump to reject any deal that would allow Iran to continue uranium enrichment, stating that no agreement should leave open a path to nuclear weapons. On May 14, Iran ratified the
UN Convention against Transnational Organized Crime as part of its efforts to meet the
FATF Action Plan requirements for improving its anti-money laundering and counter-terrorism financing system.
Trump's May 2025 proposal and Iranian response During
Donald Trump's trip to the Middle East in mid-May, he mentioned Iran on several occasions. In
Saudi Arabia, he called Iran the most destructive force in the Middle East and stated that Iran's leaders had focused on stealing their people's wealth to fund terror and bloodshed, tearing the region down. During that same visit though, he offered an olive branch to Iran, expressing his strongest willingness so far to engage in negotiations. The move was seen as a shift in US foreign policy, emphasizing that the US does not see any nation as a permanent enemy. During his next stop, Trump appealed to
Qatari's emir to use his influence to help persuade Iran to reach a deal with the US over its nuclear program, calling the situation perilous and stressing the need for a solution. Khamenei advisor
Shamkhani responded to Trump's offer and said that the Iranian government was ready to sign the nuclear deal in exchange for the quick removal of all financial sanctions, whilst at the same time criticizing Trump's rhetoric and ongoing threats, saying: "He speaks of an olive branch, but we see only barbed wire." however, Iranian officials denied having received a new US proposal and insisted they would not give up their right to enrich uranium. The Trump administration has increasingly demanded that Iran abandon uranium enrichment, making this a central issue. Khamenei rejected the proposal, dismissing this US demand as "excessive and outrageous". On the same day, Trump urged Iran to "move quickly" toward a deal, Iran held talks with European powers in
Istanbul about its nuclear negotiations with the US, with Iranian foreign minister Araghchi cautioning that reinstating UN sanctions, which had been lifted under the 2015 nuclear agreement that expired in October, could lead to "irreversible" consequences. On May 20,
CNN reported Israel was preparing to strike Iranian nuclear facilities, an action that would mark a clear break with Trump's efforts. The day after, the US imposed new measures targeting Iran's construction sector, linked to the
IRGC, and restricted 10 materials tied to its nuclear and military programs. After these mixed signals, Trump was optimistic and said that progress had been made. In the weeks leading up to the fifth round, tensions between Trump and Israeli Prime Minister
Netanyahu had increased over the US decision to engage in nuclear talks with Iran, which Israel viewed as a serious threat to its security and regional interests. Israel strongly opposed the negotiations, lobbying against diplomatic efforts and threatening unilateral military action, including potential strikes on Iranian nuclear facilities, a position critics warned could endanger diplomacy and heighten regional tensions. Iran had reportedly strengthened its air defense systems and increased military investments in preparation for a possible US or Israeli attack if negotiations failed. Iran also ordered a large amount of Chinese solid-fuel components for ballistic missiles. Iranian foreign minister Araghchi warned that any war against Iran would cause widespread destruction across the Middle East, and that the entire region would suffer if conflict erupted. Iran rejected the intelligence report as "false and baseless", calling it an attempt to create "media hype" against Iran and lacking any credibility. On June 2,
Reuters reported that Iran was preparing to decline the US proposal. After speculation that Iran might be allowed limited uranium enrichment under a possible deal, Senator
Schumer demanded that Witkoff testify before
Congress to clarify whether any such side agreement existed. The administration publicly maintained that Iran would not be permitted to enrich uranium. Khamenei responded that uranium enrichment is central to Iran's nuclear program and he rejected US demands to halt it. Although the American government had suspended new sanctions on Iran on June 2, just four days later it imposed secondary sanctions on 10 individuals and 27 financial investment companies and trading firms.
Iran's rejection of the US proposal On June 9, Iran rejected the Trump administration's proposal for a new nuclear deal but announced plans to present a counteroffer through Omani mediators. Iranian Foreign Ministry spokesperson Esmaeil Baghaei called the US proposal unacceptable and not aligned with the ongoing negotiations. The main points of disagreement included Iran's right to continue domestic uranium enrichment, the handling of its stockpiles of highly enriched uranium, and the conditions for lifting
sanctions against Iran. While Trump demanded the full dismantlement of Iran's enrichment program, Iranian leaders insisted that enrichment was non-negotiable. The latest US offer reportedly included assistance in building nuclear power reactors and allowed limited enrichment until a regional consortium facility becomes operational. A central demand from Iran was that sanctions relief must bring tangible economic benefits. Baghaei emphasized that this includes guarantees of restored banking and trade ties with other countries before any sanctions are lifted. He also urged the international community to address Israel's undeclared nuclear arsenal and prevent it from derailing negotiations. The following day, Iranian defense minister
Aziz Nasirzadeh warned that if negotiations with the US collapse and conflict erupts, Iran will target American bases in the region. He stated that all US bases in nearby countries are within reach. Trump also repeatedly threatened Iran with military action if no deal was reached. US defense secretary
Hegseth announced that the US military was getting ready in case the talks fail. On June 12, IAEA found Iran non-compliant with its nuclear obligations for the first time in 20 years. The IAEA stated that Iran's repeated failure to fully address questions about undeclared nuclear material and activities amounted to non-compliance. It also raised concerns over Iran's enriched uranium stockpile, which could be used for both reactor fuel and nuclear weapons. ==Twelve-Day War==