•
A. Clarke (Leicestershire cricketer), English cricketer •
Adam Clarke (1760–1832), British biblical scholar •
Adam Vincent Clarke, composer •
Adele Clarke (1945–2024), American sociologist •
Adline Clarke, American politician •
A. E. Clarke, architect working in Australia from the 1890s •
Alan Clarke (1935–1990), British TV and film director •
Alexander Ross Clarke (1828–1914), British geodesist •
Alf Clarke (1926–1971), English footballer •
Alfie Clarke (disambiguation), several people •
Alfred Clarke (disambiguation), several people •
Allan Clarke (footballer) (born 1946), English footballer •
Andrew Clarke (disambiguation), several people • Ann or
Anne Clarke (disambiguation) • Anthony or Tony Clarke – see
Anthony Clarke (disambiguation) •
Arianna Clarke (born 1999), Australian rules footballer •
Arthur C. Clarke (1917–2008), English science-fiction author, futurist, inventor and undersea explorer •
Ashley Clarke (1903–1994), British ambassador to Italy, founder of the Venice in Peril Fund •
Austin Clarke (novelist) (1934–2016), Barbadian novelist, essayist and short-story writer •
Austin Clarke (poet) (1896–1974), Irish poet •
Basil Clarke (1879–1947), British writer and newspaper war correspondent •
Bertie Clarke (1918–1993), West Indian cricketer •
Bethia Clarke (1867–1959), British artist • Bill or Billy Clarke – see
William Clarke (disambiguation) •
Bob Clarke (disambiguation) •
Bobbie Clarke (1940–2014), British rock drummer •
Bobby Clarke (born 1949), Canadian ice hockey player •
Brandon Clarke (born 1996), Canadian basketball player •
Brandt Clarke (born 2003), Canadian ice hockey player •
Brian Clarke (disambiguation), several people •
Bruce B. G. Clarke (born 1943), US Army officer, author and consultant •
Bruce C. Clarke (1901–1988), American general •
Buck Clarke (1933–1988), American jazz percussionist •
C. Clarke (1837 English cricketer), English cricketer •
C. Clarke (Sheffield cricketer), English cricketer •
Caitlin Clarke (1952–2004), American actress •
Cam Clarke (born 1957), American voice actor •
Campbell Clarke (1835–1902), British journalist •
Carter Clarke (1896–1987), American brigadier general •
Caspar Purdon Clarke (1846–1911), English architect and museum director •
Catherine Clarke, British historian •
Catherine Goddard Clarke (1900–1968), American Catholic writer and religious community founder •
Cecil Vandepeer Clarke (1897–1961), British soldier and inventor •
Charles Clarke (disambiguation) •
Charlotte Clarke, Scottish academic researching dementia •
Chris Clarke (disambiguation) •
Claire D. Clarke (d. 2022), American politician •
Clem S. Clarke (1897–1967), American oilman and politician •
Coty Clarke (born 1992), American basketball player in the
Israeli National League •
Cyril Clarke (1907–2000), English physician and medical researcher •
Darren Clarke (born 1968), Northern Irish golfer •
Darren Clarke, Co Louth Gaa Footballer •
David Clarke (disambiguation) •
Dean Clarke (disambiguation) •
Denzel Clarke (born 2000), Canadian baseball player •
Dominic Clarke (born 1997), Australian trampoline gymnast • Don or
Donald Clarke (disambiguation) •
Dora Clarke (1895–1989), English artist • Doug or
Douglas Clarke (disambiguation) •
Drew Clarke, Australian public servant •
Dudley Clarke (1899–1974), British intelligence officer •
Eddie Clarke (musician) (1950–2018), British guitarist and podcaster •
Edith Clarke (1883–1959), American electrical engineer and professor •
Edmund M. Clarke (1945–2020), American computer scientist •
Edward Clarke (disambiguation) •
Edwin Clarke (1919–1996), British neurologist and medical historian •
Ellis Clarke (1917–2010), lawyer, diplomat, Governor General, President of the Republic of Trinidad and Tobago •
Emilia Clarke (born 1986), English actress •
Ernest Clarke (1856–1923), English historian of agriculture •
Eva Clarke (born 1945), British-Czech Holocaust survivor •
Frank Clarke (disambiguation), also Francis and Franklin •
Frederick S. Clarke (1949-2000), American magazine publisher, editor, and writer •
Garvin Clarke (born 2001), Bahamian basketballer •
George Clarke (disambiguation) •
Gillian Clarke (born 1937), Welsh poet •
Goland Vanhalt Clarke (1875–1944), British Army brigadier-general, big game hunter, naturalist •
Gordon Luke Clarke (born 1945), New Zealand-born 1970s fashion designer •
Graeme Clarke (born 2001), American ice hockey player •
Harold Clarke (disambiguation) •
Harry Clarke (disambiguation) •
Helen Clarke (disambiguation) •
Henri Jacques Guillaume Clarke (1765–1818), Franco-Irish general under Napoleon I •
Henry Clarke (disambiguation) •
Heroy Clarke, Jamaican politician •
Horace Clarke (born 1940–2020), Virgin Islander Major League Baseball player •
Hyde Clarke (1815–1895), English engineer, philologist and author •
Ian Clarke (disambiguation) •
Jacob Augustus Lockhart Clarke (1817–1880), British neurologist •
James Clarke (disambiguation), also Jim Clarke •
Jason Clarke (born 1969), Australian actor •
Jay Clarke (disambiguation) •
Jennie Thornley Clarke (–?), American educator, writer, anthologist •
Jennifer Susan Dodd Clarke, British philanthropist and business executive •
Jennifer Ward Clarke (1935–2015), British cellist •
Jeremiah Clarke (1674–1707), English baroque composer •
Jeremy Clarke (disambiguation) •
John Clarke (disambiguation) •
Justine Clarke (born 1971), Australian actress and singer •
Katie Rose Clarke (born 1984), American musical theatre actress •
Kathleen Clarke (1878–1972), Irish political activist •
Kenneth Clarke (born 1940), British politician; Chancellor of the Exchequer •
Lennox Clarke (born 1991), English professional boxer •
Lige Clarke (1942−1975), American LGBT activist, journalist and author •
Luther W. Clarke (1825–1869), American politician •
Lydia Clarke (1923–2018), American actress and photographer •
Mae Clarke (1910–1992), American actress •
Malcolm Clarke (disambiguation) •
Marcus Clarke (1846–1881), Australian novelist •
Maree Clarke, Australian multidisciplinary artist and educator •
Martin Clarke (disambiguation) •
Mary Clarke (disambiguation) •
Matthew Clarke (disambiguation), also Matt Clarke •
Maura Clarke (1931–1980), American nun, martyr, killed in El Salvador •
Maurice Gordon Clarke (1877–1944), American football and baseball player and coach •
Megan Clarke, American cancer epidemiologist •
Michael Clarke (disambiguation), also Mike Clarke •
Mitch Clarke (born 1985), Canadian mixed martial artist •
Mitch Clarke (basketball) (born 1999), Australian basketball player •
Nancy Clarke (entrepreneur) (died 1811 or 1812), Barbadian hotelier and free woman of colour •
Naomi Clarke, (born 1982), New Zealand soccer player •
Nevelle Clarke (born 1996), American football player •
Nig Clarke (1882–1949), American baseball player •
Nigel Clarke (disambiguation), several people •
Nobby Clarke (1907–1981), English footballer •
Noel Clarke (born 1975), British actor, director and screenwriter •
Norm Clarke (1942–2025), American journalist •
Olive Clarke (1922–2023), English farmer and public figure •
Patrick Clarke, (born 1965), Irish actor, director, producer and screenwriter •
Pauline Clarke (1921–2013), British writer •
Peter Clarke (disambiguation) •
Philip Clarke (disambiguation) •
Powhatan Henry Clarke (1862–1893), United States Army first lieutenant, recipient of the Medal of Honor during the Indian Wars •
Ralph Clarke (mayor) (died 1660), mayor of Chesterfield, 1598 •
Rebecca Clarke (disambiguation) •
Richard Clarke (disambiguation) •
Robert Clarke (disambiguation) •
Roger Clarke (disambiguation) •
Ronald Clarke (disambiguation) •
Rotnei Clarke (born 1989), American basketball player •
Rozlyne Clarke (born 1967), Australian make-up artist, musical theatre actor and dance music singer •
Ryan Clarke (disambiguation) •
Samuel Clarke (disambiguation) •
Sarah Clarke (disambiguation) •
Sharon D. Clarke (born 1966), English actress and singer •
Sidney Clarke (1831–1909), American politician •
Simon Clarke (disambiguation) •
Stanley Clarke (born 1951), American double bass and bass guitar musician • Stephen or Steve Clarke – see
Stephen Clark (disambiguation) •
Susanna Clarke (born 1959), British novelist (
Jonathan Strange & Mr Norrell) •
Sylvester Clarke, (1954–1999), West Indian cricketer •
Taylor Clarke (born 1993), American baseball player •
Terrel E. Clarke (1920–1997), American businessman and politician •
Theo Clarke (born 1985), British Member of Parliament elected 2019 •
Theophilus Clarke (1776?–1831), English painter • Tom or
Thomas Clarke (disambiguation) •
Troy Clarke (disambiguation) •
Vince Clarke (born 1960), British musician with the band Erasure •
Wayne Clarke (footballer) (born 1961), English former footballer •
William Clarke (disambiguation) •
Yvette D. Clarke (born 1964), American politician, member of the United States House of Representatives •
Hannah Clarke/Baxter (1988–2020), Australian sportsperson and murder victim ==Fictional characters==