•
Dallas Buyers Club (2013) – cocaine, alcohol, methamphetamine, zidovudine, zalcitabine, peptide T •
Danger Diabolik (1968) – cannabis • ''
Darwin's Nightmare'' (2004) – glue (Toluene) •
The Day of the Beast (1995) – LSD •
Daymaker (2007) – cocaine, MDMA, LSD, cannabis •
Days of Wine and Roses (film) (1962) – alcohol •
Dazed and Confused (1993) – alcohol, cannabis, LSD •
Dead Presidents (1995) – Heroin, morphine •
Dead Man (1995) – peyote • ''
Dead Man's Shoes'' (2004) – cocaine, cannabis, LSD, MDMA •
Dead Ringers (1988) – various prescription drugs (dextroamphetamine and opioids) •
Deadly Addiction (1988) – cocaine •
Death at a Funeral (2010) – mescaline, Valium, ketamine (mentioned), acid (the pills in the Valium bottle) •
The Death of Richie (1977) – barbiturates, others •
Death Wish 2 (1982) – cannabis, PCP •
Death Wish 4: The Crackdown (1987) – crack cocaine •
The Decline of Western Civilization Part II: The Metal Years •
Deep Cover (1992) – crack cocaine •
Delta Force 2: The Colombian Connection (1990) – cocaine •
Den Siste Revejakta (2008) – hashish, cannabis, heroin, LSD •
The Departed (2006) – oxycodone, lorazepam, heroin, cocaine •
Deprisa, Deprisa (1981) – heroin •
Descending the Mountain (2021) – psilocybin (documentary about a study by
Franz X. Vollenweider) •
Detroit Rock City (1999) – cannabis, psychedelic mushrooms •
Dev.D (2009) – cocaine, LSD, ecstasy, various pills • ''
Devil's Harvest'' (1942) – cannabis • ''
The Devil's Rejects'' (2005) – cocaine, cannabis •
Dick (1999) – cannabis, Quaaludes •
Dirty Grandpa (2016) – crack cocaine, xanax, cannabis •
District 13 (2004) – cocaine, cannabis •
DMT: The Spirit Molecule (2010) – DMT documentary •
Domino (2005) – mescaline, cannabis, cocaine •
Donkey Punch (2008) – ketamine, Methamphetamine, MDMA, cannabis • ''
Don's Plum'' (2001) – heroin, cannabis • ''
Don't Be a Menace to South Central While Drinking Your Juice in the Hood'' (1996) – cannabis, crack cocaine • ''
Don't Tell Mom the Babysitter's Dead'' (1991) – cannabis •
The Doors (1991) – LSD, cocaine, heroin, cannabis, peyote •
Dope Sick Love (2005) – heroin, crack cocaine •
Down in the Valley (2005) – MDMA •
Dragon Eyes (2012) – crack, heroin •
Dream with the Fishes (1997) – heroin, LSD •
Dreamseller (2007) – heroin •
Dredd (2012) – fictional drug Slo-mo (slows the user's perception to 1%) •
The Drug Traffic (1923) •
Drugstore Cowboy (1989) – cocaine, hydromorphone, oxymorphone, morphine, amphetamines, valium (diazepam), methamphetamine, heroin • ''
Dude, Where's My Car?'' (2000) – cannabis •
Due Date (2010) – cannabis and vicodin •
The Dukes of Hazzard (2005) – cannabis •
Drug Call (2024) – heroin, LSD == E ==