•
Isabelle of Luxembourg (1247–1298), a daughter of Henry V of Luxembourg and his wife Margaret of Bar •
Isabelle of Orléans (disambiguation) •
Princess Isabelle (disambiguation) •
Isabelle Abiera (born 1992), a Filipina actress and model •
Isabelle Adjani (born 1955), a French film actress and singer •
Isabelle Antena, a French singer •
Isabelle Arnould (born 1970), a Belgian female freestyle swimmer •
Isabelle Aubret (born 1938), a French singer •
Isabelle Autissier (born 1956), a French sailor, navigator, writer and broadcaster •
Isabelle Amyes (born 1950), an English actress •
Isabelle Bean (1862 – 1939), an Australian nurse, theosophist and feminist •
Isabelle Blais, a Canadian actress and musician •
Isabelle Blanc (born 1975), a French snowboarder and Olympic champion •
Isabelle Boulay (born 1972), a francophone Canadian pop singer •
Isabelle Boulogne (born 1971), a French sprint canoer •
Isabelle Brasseur (born 1970), a Canadian figure skater •
Isabelle Breitman (born 1959), a French actress and director •
Isabelle von Bueltzingsloewen (born 1964), a French academic and historian •
Isabelle Buret, a French telecommunications and space science engineer •
Isabelle Le Callennec (born 1966), French politician •
Isabelle Rauch (born 1968), French politician •
Isabelle Carbonell, a Belgio-Uruguayan documentary photographer and filmmaker •
Isabelle Caro, a French model suffering from severe anorexia nervosa •
Isabelle Carré (born 1971), a French actress •
Isabelle Champmoreau (born 1974), a New Caledonian politician •
Isabelle Charest (born 1971), a Canadian short track speed skater •
Isabelle Chartrand (born 1978), a Canadian ice hockey player •
Isabelle Cheng (born 1970), an intelligence agent •
Isabelle Collin Dufresne (aka Ultra Violet, 1935–2014), a French-American artist •
Isabelle Corey (1939–2011), a French film actress •
Isabelle Coutant-Peyre (born 1952), a French lawyer •
Isabelle Daniels (1937–2017), an American athlete, who mainly competed in the 100 metres •
Isabelle de Charrière (1740–1805), a Dutch-born writer of the Enlightenment •
Isabelle de Craon (c.1212–??), a French noblewoman •
Isabelle Debré (born 1957), a member of the Senate of France •
Isabelle Delobel (born 1978), a French figure skater •
Isabelle Delorme (1900–1991), a Canadian composer, pianist and music educator •
Isabelle de Meulan (c. 1148 – 1220), a French noblewoman •
Isabelle Demongeot (born 1966), a former French professional tennis player •
Isabelle de Montolieu (1751–1832), a Swiss novelist and translator •
Isabelle Despres, a French slalom canoer •
Isabelle Devaluez (born 1966), a French discus thrower •
Isabelle Diks (born 1965), a Dutch GreenLeft politician •
Isabelle Dinoire (born 1967), the first person to undergo a partial face transplant •
Isabelle Duchesnay (born 1963), an ice dancer who competed for both Canada and France •
Isabelle Durant (born 1954), a Belgian politician, member of the Ecolo party •
Isabelle Eberhardt (1877–1904), a Swiss-Algerian explorer and writer •
Isabelle Ferron (born 1967), an actress in both film and stage •
Isabelle Fijalkowski (born 1972), a French basketball player •
Isabelle Flory, a French violinist •
Isabelle Jane Foulkes (1970–2001), Anglo-Welsh artist, textile designer and disability campaigner •
Isabelle Fuhrman (born 1997), an American teen actress •
Isabelle Gatti de Gamond (1839–1905), an Italo-Belgian educationalist, feminist and politician •
Isabelle Gaudeuille (born 1954), Central African Republic lawyer and politician •
Isabelle Goldenson (1920–2005), American lobbyist and philanthropist •
Isabelle Guyon (born 1961), French-born researcher in machine learning •
Isabelle Haak (born 1999), Swedish volleyball player •
Isabelle Bowen Henderson (1899–1969), American painter and floriculturist •
Isabelle Holland (1920–2002), an author of children and adult fiction books •
Isabelle Huppert (born 1953), a French actress •
Isabelle Keith (1898–1979), an American actress •
Isabelle Kridluar (1954–2018), Inuk artist who lived by Repulse Bay, Nunavut, Canada •
Isabelle LaMal (1886–1952), an American film actress •
Isabelle Laville (died 1987), French murder victim •
Isabelle Lendl (born 1991), an American amateur golfer •
Isabelle Li, Singaporean table tennis player •
Isabelle Liberman (1918–1990), an American psychologist •
Isabelle Lucas (1927–1997), a Canadian-born British actress and singer •
Isabelle Mancini (born 1967), a French cross country skier •
Isabelle Mercier (born 1975), a Canadian professional poker player •
Isabelle E. Merry (1907–2000), Australian Congregational minister and chaplain •
Isabelle Mir (born 1949), a French former Alpine skier •
Isabelle Morneau (born 1976), a defender on the Canada women's national soccer team •
Isabelle Mouthon-Michellys (born 1966), a French athlete •
Isabelle Nanty (born 1962), a French actress and film director •
Isabelle Nylander (born 1990), a Swedish figure skater •
Isabelle Olivieri (1957–2016), French biologist, specialising in evolutionary sciences, genetics and population biology •
Isabelle Pasco (born 1966), a French actress and model •
Isabelle Pasquet (born 1962), member of the Senate of France •
Isabelle Pearson (born 1981), Canadian judoka •
Isabelle Peretz, a Professor of Psychology at the University of Montreal •
Isabelle Périgault (born 1971), French politician •
Isabelle Pieman (born 1983), Belgian figure skater •
Isabelle Pinson (1769–1855), French genre painter and portraitist •
Isabelle Rampling (born 1985), Canadian synchronized swimmer •
Isabelle Rezazadeh, also known as Rezz, a Canadian DJ and record producer •
Isabelle Romée (1377–1458), the mother of Joan of Arc •
Isabelle Sadoyan (1928–2017), French actress •
Isabelle Sandy (1884–1975), French poet and writer •
Isabelle Schad (born 1970), German dancer and choreographer •
Isabelle Severino (born 1980), French gymnast and actress •
Isabelle Simonis (born 1967), Belgian politician from the Socialist Party •
Isabelle Stengers (born 1949), Belgian philosopher and the daughter of the historian Jean Stengers •
Isabelle Stoehr (born 1979), French professional squash player •
Isabelle Stone (1868–1944), American physicist •
Isabelle Story (1887–1970), American writer and editor •
Isabelle Thompson (1891–1946), Hawaiian-American teacher and politician •
Isabelle Turcotte Baird (born 1970), Canadian athlete •
Isabelle Urquhart (1865–1907), American stage actress •
Isabelle Vasseur (born 1959), member of the National Assembly of France •
Isabelle Valentin (born 1962), French politician •
Isabelle Vandre (born 1989), German politician •
Isabelle Vengerova (1877–1956), a Russian-born American pianist and music teacher •
Isabelle Wendling (born 1971), a French handball player •
Isabelle Wéry, a Belgian actress and writer •
Isabelle Westbury (born 1990), an English cricketer •
Isabelle White (1894–1972), a British diver •
Isabelle Yacoubou (born 1986), French, of Bénin origin, professional basketball player
Fictional characters •
Isabelle (Animal Crossing), an anthropomorphic dog character who was introduced as the mayor's assistant in the
Nintendo 3DS game title
Animal Crossing: New Leaf •
Isabelle (comics), a Belgian comic book series • Isabelle Andersson, character in the
Sune book series, Sune's younger sister • Isabelle of Cornwall, the mother of
Tristan in Arthurian legend • Isabelle Kruger, a character played by
Marion Cotillard in the 2005 film
The Black Box •
Isabelle Lightwood, character in
The Mortal Instruments series and
Shadowhunters TV series based on the novel • Isabelle Palmer,
American Girl character •
Isabelle Tyler, a character on the USA Network science fiction television series
The 4400