"It's Gonna Be Me" first appeared on the US
Top 40 Tracks chart on the May 6, 2000, issue of
Billboard at number 33, after it was distributed as a
promotional record. It was then released in continental Europe on June 12, 2000. Consequently, this caused "It's Gonna Be Me" to reach number one on the July 29, 2000, issue, scanning 91,000 units. It was the second song released by
Jive Records to reach number one since
Britney Spears' "
...Baby One More Time" in 1999, as they were one of the only singles to be released on
CD and
cassette formats. The song remained at number one on the Hot 100 for two consecutive weeks, charting from the July 29–August 5, 2000, dated issues of
Billboard. It was the only number one single released by NSYNC, despite six of their singles appearing in the top 10 of the chart. The song also reached number one on the
Mainstream Top 40 after spending eight weeks on the chart, dethroning Spears' "
Oops!... I Did It Again" (2000). In Canada, it debuted at number 18 on the
RPM Top 100 Singles chart dated June 5, 2000. The song peaked at number one on the July 10, 2000, issue, replacing "Oops!... I Did It Again" which had then spent 11 weeks on the chart. "It's Gonna Be Me" was certified platinum by
Music Canada (MC) on August 31, 2023, for track-equivalent sales of 80,000 units in the country. "It's Gonna Be Me" bowed on the
UK Singles Chart at number nine after charting for 12 weeks. It was certified gold by the
British Phonographic Industry (BPI) on December 12, 2025, for selling 400,000 equivalent sales units. On the Swedish
Sverigetopplistan chart, the song peaked at number six on August 31, 2000, and remained for 10 weeks before receiving a gold certification for sales of 15,000 equivalent units. It reached the top 20 in Italy, Norway, and Scotland. In Australia, "It's Gonna Be Me" debuted at number 15 on the
ARIA Singles Chart on June 25, 2000. It peaked at number 11 and charted for 12 weeks, before receiving a platinum certification by the
Australian Recording Industry Association (ARIA) for shipping over 70,000 equivalent units. The song peaked at number seven on the
New Zealand Singles Chart after charting for 19 weeks, where it was certified gold by
Recorded Music NZ (RMNZ) for track-equivalent sales of 5,000 units in the country. ==Music video==