After graduating from the
National Taiwan University College of Medicine in June 1986, Ko briefly worked as an
anesthetist at a local Hsinchu hospital. In 1994, Ko, with an invitation from Chu Shu-hsun, helped found NTU's first organ transplant team, with the goal of performing
heart transplants. Hoping to increase the transplant success rate, Ko introduced
ECMO treatment from the US, and improved the transplant success rate from 19% to 51%. On 30 January 2008, Ko set a world record of 117 consecutive days for keeping a patient alive using ECMO. Using US treatment standards as a guide, Ko established a set of standards for organ transplant procedures that was later promulgated throughout Taiwan by the
Department of Health. On 15 July 2006, Ko wrote an article for the
Min Sheng Daily titled "Reflections, Errors, and Apologies: Chao Chien-ming" that received considerable media attention and led to a number of politics-related interviews. On 18 November, Ko used ECMO to save the life of Shirley Shaw, wife of
Taichung Mayor Jason Hu, who had fallen into a coma after a car accident. This incident and the media attention it drew caused Ko Wen-je to become a household name. In 2010, Ko introduced the concept of
integrated care to Taiwan, and established the Integrated Care Unit at NTU Hospital with the aim of reducing treatment cost and improving quality of treatment and quality of life for the attendant doctors and nurses. Ko directed the emergency care team that treated
Sean Lien for critical wounds after he was shot in the face with a 9mm pistol on 26 November. Lien recovered quickly, which led the media to speculate about the veracity of his story, but Ko came forward to verify his claims. In 2013, Ko's emergency trauma care student Tseng Yu-tzu was hit by a drunk driver and sustained major trauma. Ko went to the hospital as soon as he was notified and oversaw her treatment, but she died.
Relationship with Chen Shui-bian When
Chen Shui-bian was elected as Taipei City Mayor in 1994, Ko provided support to him from the medical community. He also supported Chen in the
2000 presidential election, when he took two weeks off work to support Chen's fundraising efforts. Ko is also a long-time member of the "Friends of A-bian Club". In April 2012, Ko enrolled in a course at , a school originally founded by Chen in 2003. In response to the political nature of the course and its timing, Ko explained that he enrolled because he had been asked to, and that he would not sign a petition requesting that Chen be pardoned for
corruption charges. When Chen Shui-bian's health declined in prison, Ko organized a medical team for him. Around June 2012, Ko and other prominent members of the medical community started a petition asking that Chen be released for medical treatment. == Mayoral elections ==