MarketHaplogroup R (mtDNA)
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Haplogroup R (mtDNA)

Haplogroup R is a widely distributed human mitochondrial DNA (mtDNA) haplogroup. Haplogroup R is associated with the peopling of Eurasia after about 70,000 years ago, and is distributed in modern populations throughout the world outside of sub-Saharan Africa.

Origin
Soares et al. (2009) estimate the age of haplogroup R at roughly 50,000 to 70,000 years ago. It has been suggested that the early lineage of haplogroups M, N and R along the coastal route during the period of roughly 70,000 to 60,000 years ago. The northern route out of Africa is another possibility, where the expansion of haplogroup R may originate from Southeast Asia. Haplogroup R has wide diversity and antiquity in the indigenous population of South Asia. Tribes and castes of Western and Southern India show higher diversity than the other regions, possibly suggesting their autochthonous status. Larruga et al. (2017) found mtDNA R spread to Eurasia and Australia from a core area along the Southeast Asian coast. ==Archaeogenetics==
Archaeogenetics
The Ust'-Ishim man of Siberia, dated ca. 45,000 years old, belongs to haplogroup R* (formerly classified as U*). Haplogroup R has also been observed among Egyptian mummies excavated at the Abusir archaeological site in Lower Egypt, which date from the late New Kingdom of Egypt, the Ptolemaic Kingdom, and Roman Egypt. Subclade R2 was observed in the remains of a Neolithic human from western Iran in Tepe Abdul Hosein. ==Distribution==
Distribution
Haplogroup R and its descendants are distributed all over Australasia, Americas, Southeast Asia, South Asia, Central Asia, West Asia, East Asia, Europe, North Africa and Horn of Africa. The basal R* clade is found among the Soqotri (1.2%), as well as in Northeast Africa (1.5%), the Middle East (0.8%), the Near East (0.8%), and the Arabian Peninsula (0.3%). SubcladesHaplogroup RR0 or pre-HVR0a or (preHV)1: Occurs commonly in the Arabian peninsula, with its highest frequency observed among the Soqotri. Moderate frequencies found in North Africa, the Horn of Africa, and Central Asia. • HV: It is a west Eurasian haplogroup mainly found throughout the Middle East, including Iran. It is also found in North Africa, Central Asia and South Asia. • V: Found at moderately low frequencies around Europe; the highest frequency is in the Sami people 40%. • HV1: Mainly in the Middle East. • HV2: Mainly in South Asia. • H: In West Eurasia. It is the most common mtDNA haplogroup in Europe. • R1 • R1a* (3337): Found in Brahmins from Uttar Pradesh (India). • R1b1: Observed in Bulgaria, Armenia (including an ancient specimen), and India • R1b1a: Observed in Uyghurs • R1b1b: Observed in Finland (including Finland Swedes) • R1b2 • R1b2a: Observed in Yakuts • R1b2b: Observed in Uyghurs • pre-JT or R2'JT • R2: Present in low frequencies in Middle East, Pakistan, and India. • T: The highest frequency is in the Caspian region (Caucasus, Northern Iran, Turkmenistan). Middle East, Central Asia, Pakistan and North Africa. Small frequency in the Horn of Africa and India. • R3: Found in Armenia. Also observed in an ancient individual from Hungary, dating to 7000 years ago • R5: Widely spread in the Indian subcontinent. Specially in Madhya Pradesh (India) at 17%. • R5a • R5a1: Found within the Indo-European speaking populations of India. • R5a2: Specially among Dravidic groups of India and Sri Lanka. • '''R6'7''' (16362) The most important presence is among Austroasiatic language-speakers from India (10%). • R7a: Mainly in East India, specially in Santals from Bihar and Jharkhand. • R8a: Found mainly in Orissa and Andhra Pradesh (India). • R8b: In Orissa, Gujarat, Andhra Pradesh (India). • R9 (16304) • R9b: It appears mostly in Southeast Asia. Found all over Indonesia, in Indochina, Malaysia, in Aboriginal Malays like Semelai at 28% and Temuan 21%. • (249d) • R9c: All over the Malay Archipelago and Taiwan. Mainly in Batak (Palawan) at 58%, the Tsou of Taiwan (22.9%), and Alor (Indonesia) at 11%. • F: Fairly common in East Asia and Southeast Asia. Higher frequencies occur in some areas like Nicobar at 50% and Arunachal Pradesh 31% (India), There is also an important frequency in Taiwanese aborigines, Guangdong (China), Maluku (Indonesia), Thailand and Vietnam. • R11'B (16189) • R11: Found in China, mainly in Lahu people from Yunnan at 12.5%. Also in Japan, Korea, Chams, and Rajasthan (India). • B • B4: It is found often in East Asia, Southeast Asia, Polynesia, Melanesia, Micronesia, Madagascar and Indigenous peoples of the Americas. • B5: Spread in East Asia and Southeast Asia. • R24: Found in Philippines. • R12'21 • R12: Found in Australia. • R21: In indigenous peoples of Malaysia like Jahai Negritos at 63% • R14: Found in Papua New Guinea and in Austronesian speakers of East Timor and Lembata. • R22 or R12: Very frequent in the Shompen (10/29 = 34.5%). Elsewhere found mainly in south-central Indonesia (11.4% Mataram, 8.0% Waingapu, 7.3% Bali, 1.9% Borneo) and in Cham of Bình Thuận, Vietnam (7/168 = 4.2%), with singleton or sporadic occurrences in Thailand, Sumatra, Java, Sulawesi, and Alor. and Sinhalese people from Sri Lanka. Also found in Maluku, Nusa Tenggara and Polynesia. • P2'10 • P2: In Melanesia, • P3: In Australia and Melanesia. • U • U1: It appears mostly in the Middle East and Caucasus. Found from India to the Mediterranean and to the rest of Europe. • U5: Approximately 11% of total Europeans and 10% of European-Americans. The highest frequency is in the Sami people. Highest frequencies of the subclade occur among Algerian Berbers (29%) and Egyptian Copts (27.6%). U6 has also been found among Iberomaurusian specimens dating from the Epipaleolithic at the Taforalt prehistoric site. • U2'3'4'7'8'9 (1811): Widely spread in West Eurasia and the Indian subcontinent. • U8 • K ==Tree==
Tree
This phylogenetic tree of haplogroup R subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation Guinea • R9b1 - China, Uyghur, Thailand (Mon in Central Thailand, Thai in Western Thailand), Laos (Lao in Vientiane), Vietnam (La Hủ), Denmark • R9b1a • R9b1a1 - Philippines (Mamanwa) • R9b1a1a - China, Thailand (Karen and Thai Lue in Northern Thailand, Lao Isan in Roi Et Province, Thai in Central Thailand and Eastern Thailand), Cambodia (Banteay Meanchey), Malaysia (Semelai, aboriginal Malay), Singapore, Indonesia (Tengger, Palembang, Padang, Manado), Vietnam (Giarai) • R9b1a2 - Taiwan (Tsou), Thailand (Lao Isan in Loei Province, Thai in Western Thailand) • R9b1a2a - China (Han from Tai'an, etc.), Vietnam (Tay, etc.), Russia (Tubalar) • R9b1a2b - China, Taiwan (Minnan, Hakka), Vietnam (Tay), Thailand (Khon Mueang from Chiang Rai Province, Tai Khuen from Northern Thailand) • R9b1a3 - Thailand, China (Han, Dai), Vietnam (Dao, Nùng, etc.), Kazakhstan • R9b1b - China, Vietnam, Cambodia (Siem Reap), Thailand (Khon Mueang from Chiang Mai Province, Tai Yuan from Central Thailand, Mon from Northern Thailand) • R9b2 - Thailand, Cambodia, Vietnam • R9c - China (Barghut from Hulun Buir), Taiwan • R9c1 • R9c1a - Philippines, Indonesia, Taiwan (Makatao), Thailand (Khon Mueang from Chiang Rai Province) • R9c1a1 - Taiwan (Makatao, Rukai, Puyuma, etc.), Guam • R9c1a2 - Taiwan (Tsou, Bunun) • R9c1a3 - Philippines (Batak of Palawan) • R9c1b • R9c1b1 - China (Han), Vietnam (Kinh, Dao), Thailand (Tai Dam in Kanchanaburi Province, Khon Mueang in Mae Hong Son Province, Tai Yuan in Northern Thailand, Thai Lue in Northern Thailand), Myanmar • R9c1b2 - Thailand (Khon Mueang in Chiang Rai Province), Taiwan (Makatao, etc.), Philippines (Ifugao, Bugkalot), East Timor • F • R-T16189C! • R11'B (16189) • R11'B6 • R11 • R11a • R11b • R11b1 • R11b1a • R11b1b • B6 • B6a • B6a1 • B6a1a • B • B4'5 • R24 • R24a • R12'21 • R12 • R21 • R14 • R22 • R23 • R30 • R30a • R30a1 • R30a1a • R30a1b • R30a1b1 • R30a1c • R30b • R30b1 • R30b2 • R30b2a • R31 • R31a • R31a1 • R31b • R32 • PU ==References==
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