The plight of Argentina forced Prebisch to reexamine the principle of
comparative advantage described by
David Ricardo, marking the creation of a new school of economic thought in the late 1940s. Prebisch separated out the purely theoretical aspects of economics from the actual practice of trade and the power structures that underlie trading institutions and agreements. His resulting division of the world into the economic "centre", consisting of industrialised nations such as the U.S., and the "periphery", consisting of primary producers, remains used to this day. As president of the
Central Bank of Argentina he had noticed that during the Great Depression the prices of primary products, such as agricultural goods, fell much more than the prices of manufactured secondary products. However, he and his colleagues were unable to specify the exact mechanism for the difference, beyond hypothesizing that supply conditions of primary and secondary goods were different in that while farmers planted the same amount every year regardless of the price they would get, manufacturers were able to reduce or increase capacity to respond to expected changes in demand. However, these ideas remained unformed until he was appointed executive director of the
Economic Commission for Latin America (ECLA or CEPAL) in 1950. Due to Prebisch's influence the ECLA became the center of
Third World activism in the UN, giving birth to the Latin American school of
structuralist economics. While many scholars perceive Prebisch as supporting
import substitution industrialization (ISI), in which a nation progressively changes its imports and internal production, focusing on industrialization, at the cost of imported "superfluous" goods in favor of capital and intermediate goods for a given period of time, Prebisch criticized protectionism, especially that practiced by
Juan Perón in Argentina, since 1956 and ISI since at least 1963. He advocated industrialization and economic cooperation, including through trade, among developing countries.
The International Institute of Social Studies (ISS) awarded its Honorary Fellowship to Raúl Prebisch in 1977. ==UNCTAD secretary-general==