According to Perso-Arabic sources, Ctesiphon, the capital of the Sasanian Empire, was greatly enlarged and flourished during their rule, thus turning into a metropolis, which was known in Arabic as al-Mada'in, and in
Aramaic as Mahoza. The oldest inhabited places of al-Mada'in were on its eastern side, which in Arabic sources is called "the Old City", where the residence of the Sasanians, known as the
White Palace, was located. The southern side of al-Mada'in was known as Aspanbar, which was known by its prominent halls, riches, games, stables, and baths. The western side was known as Veh-Ardashir (meaning "the good city of Ardashir" in
Middle Persian), known as Mahoza by the Jews, Kokhe by the Christians, and Behrasir by the Arabs. Veh-Ardashir was populated by many wealthy Jews, and was the seat of the
Church of the East patriarch. To the south of Veh-Ardashir was
Valashabad. In 495, during the turbulent reign of Emperor
Kavad I, Mahoza (as the Jews called the city) was the scene of a Jewish revolt led by
Exilarch Mar-Zutra II. After the king denied Jews the right to organize their own militia, Mar-Zutra took advantage of the confusion into which
Mazdak's communistic attempts had plunged Persia and led a successful military revolt that achieved political independence for the Jews of Mahoza. The Jewish state lasted seven years until 502 CE, when Kavad finally defeated Mar-Zutra and punished him with crucifixion on the bridge of Mahoza. In 540,
Khosrow I (r. 531–579) resettled captives from
Antioch to the south of Aspanbur, a place which became known as
Weh Antiok Khosrow, a
Middle Persian name meaning "better than Antioch, Khosrow built this". It was known by the locals of the place as Rumagan ("town of the Romans"), while the Arabs knew it as al-Rumiya (also spelled Rumiya). In 590, a member of the
House of Mihran,
Bahram Chobin repelled the newly ascended Sasanian ruler
Khosrow II from Iraq, and conquered the region. One year later, Khosrau II, with aid from the
Byzantine Empire, reconquered his domains. During his reign, some of the great fame of al-Mada'in decreased, due to the popularity of Khosrau's new winter residence, Dastagerd. In 628, a deadly plague hit al-Mada'in and the rest of the western part of the Sasanian Empire, which even killed Khosrau's son and successor,
Kavadh II. In 629, al-Mada'in was briefly under the control of Mihranid usurper
Shahrbaraz, but the latter was shortly assassinated by the supporters of Khosrau II's daughter, the
banbishn Boran. Al-Mada'in then continued to be involved in constant fighting between two factions of the Sasanian Empire, the Pahlav (Parthian) faction under the
House of Ispahbudhan and the Parsig (Persian) faction under
Piruz Khosrow. == Rashidun and Umayyad period ==