Freshman season As a freshman, Diggins became the fourth Indiana native to join the Irish roster in 2009–10, and she was one of three Miss Basketball honorees on the 2009–10 Notre Dame roster. On November 15, 2009, Diggins made her collegiate debut for Notre Dame, recording 14 points, eight rebounds, five assists and four steals in a 102–57 win over Arkansas-Pine Bluff. During her freshman year, she set four Notre Dame freshman records. Her total points scored (484) were the fourth best ever by a freshman, and her 112 assists were the third most by a freshman. On March 23, Diggins recorded 31 points, six assists, and seven steals in an 84–66 win over 10th-
seeded Vermont in the second round of the
2010 NCAA tournament. Her 31 points were the most by a Notre Dame player in their tournament debut.
Sophomore season Diggins rose to national prominence in her sophomore year, leading the Irish to the second championship game appearance in school history, ten years after Notre Dame captured the
national title in 2001. Diggins became the second Notre Dame women's basketball player to reach the 1,000-point milestone before the end of her sophomore season. She scored then season-high 24 points in a 73–59 win over fourth-ranked
Tennessee in the
Elite Eight to help Notre Dame reach its 3rd
Final Four ever. She was recognized as MOP of the
NCAA Dayton Regional. In the Final Four, Diggins recorded season-high 28 points, six assists, four rebounds, and 2 steals in a 72–63 victory against top-seeded
UConn, the defending champions. In a 76–70 loss to
Texas A&M Aggies at the national championship game, Diggins posted 23 points, 3 rebounds, 3 assists, 4 steals, and was named to the
Final Four All-Tournament Team. However, she committed 6 turnovers, the last one ending Notre Dame's chances for good as the game clock wound down. As the Associated Press reported, "Diggins, fighting back tears, said the Irish couldn't handle
A&M's pressure. 'We turned it over too much. I don't know if it was nerves or what,' she said. 'We just didn't handle the pressure.'" Diggins was a third-team All-American: she earned third-team All-American honors from the AP and the USBWA, and made the
State Farm Coaches All-America Team.
Junior season In her junior season, Diggins became the fourth
NCAA Division I player in the past decade (since 2001–02) to register 600 points, 200 assists and 100 steals in a single season. She set a school record with 102 steals, while her 222 assists were third-most on the Notre Dame single-season list, and her 657 points ranked fourth on the school's single-season chart. After leading Notre Dame to the
Big East regular-season title, she was named
Big East Player of the Year. She was also a unanimous first-team All-Big East. On March 27, at the Elite Eight of the NCAA Tournament, Diggins recorded the first triple-double in Notre Dame postseason history with 22 points, 10 rebounds and 11 assists against
Maryland. In their next game against
UConn, she scored 19 points en route to earning their second straight championship appearance. In the national championship game, Diggins scored 20 as the Irish lost to Baylor 80–61. Diggins was a unanimous first-team
All-American: she earned first-team All-American honors from the AP and the USBWA, and made the
Women's Basketball Coaches Association (WBCA) Coaches' All-America Team. She was the first Notre Dame to win the
Nancy Lieberman Award as the top
point guard in the nation.
Senior season In her final season at Notre Dame, Diggins posted career-high 33 points and five assists in a 77–67 victory over
Tennessee. On February 24, Diggins recorded her second career triple-double with 17 points, 10 rebounds and 10 assists against DePaul. Diggins recorded 225 assists, the third most assists in school history. Her 114 steals was the most in a single season history. At the end of the regular season, she was named
Big East Player of the Year for the second straight year and unanimous First Team All-
Big East. In the
Big East Tournament, Diggins was named to the All-Tournament team after leading the Irish to their first Big East championship game victory. She recorded 12 points, 6 assists, 5 steals and 3 rebounds defeating the
UConn Huskies, came up with decisive steal with eight seconds left in a tie game, then weaved through three Connecticut defenders before passing off to
Natalie Achonwa for a game-winning layup with 1.8 seconds remaining. Diggins scored a game-high 27 points in an 87–76 win over second-seeded
Duke in the
Elite Eight to help Notre Dame reach its 3rd straight
Final Four. She was recognized as MOP of the Norfolk Regional. At the
Final Four, Notre Dame was defeated by
Big East rival
UConn, 83–65, and finished the season with a 35–2 record. Diggins was named the
Nancy Lieberman Award becoming the third player to win the award twice; was named a first-team All-American by the
Associated Press and the USBWA, with the
AP vote being unanimous. Diggins is the only Notre Dame basketball player (either gender) and one of only six
NCAA Division I players since 1999–2000 to compile 2,000 points/500 rebounds/500 assists/300 steals in her career. She finished her career ranking first in points, steals, free throws made, free throws attempted, games started, minutes played, double-figure scoring games and triple-doubles, and second in school history for career assists, field goals made, field goals attempted and games played ==Professional career==