Years ago, the Intergalactic Evil Wizard Alliance, led by
Gargamel's brother, Razamel, attempted to use four magic books to rule the world with evil and destroy all the goodness in the universe. However,
Papa Smurf rescues one of the books, Jaunty, and hides her in Smurf Village. In the present, an unnamed Smurf, dubbed No Name Smurf, is new to Smurf Village. While wandering through a forest, he seemingly gains magic powers by wishing for them. At Smurf Village, No Name shows off his supposed powers to Papa Smurf, causing Razamel to detect Smurf Village and have his henchmen Joel send a portal to capture Papa Smurf. No Name,
Smurfette, Vanity, Hefty, Worry, Brainy, Grouchy and Turtle set off to find Ken, Papa's brother, heading to
Paris, in Earth, to do so. The Smurfs meet a group called the International Neighborhood Watch Smurfs led by Ken's daughter, Moxie. They lead them to their base hidden inside of a disco ball where they meet Ken who agrees to help them. No Name uses his supposed magic to create a portal to Razamel's castle, where the Smurfs enter. However, a force field installed on the castle bounces them to the portal convergence in the Australian
outback. While there, they meet the Snooterpoots, hairy creatures who pickpocket items from multiverse travelers, and Mama Poot, the leader of the Snooterpoots, tells the Smurfs of the Alliance's plan. Feeling awful for causing it, No Name runs away from the Snooterpoots. While Smurfette comforts him, Razamel captures the rest of the Smurfs, as well as the Snooterpoots. Mama Poot, determined to save her children, rallies up No Name and Smurfette and brings them to
Munich to stop him. As Razamel is about to smash Papa Smurf and Smurfette, No Name and Mama Poot enter the room. Jaunty is revealed to be doing the magic for No Name. Joel then captures the three, while Razamel corrupts Jaunty, flying away with her after disowning Gargamel. Angered, he saves the Smurfs, and escapes with them. Papa Smurf comforts the others by sharing his story about his brother Ron, who sacrificed himself to save Jaunty. Razamel enters a meeting of the Alliance, where he tells them about his evil misdeeds. When they ignore him, he traps them inside a water dispenser and uses the four evil books to rule the universe. However, Gargamel and the Smurfs intervene by crashing into the scene with a flying car. Smurfette reverts Jaunty back to good after most of the other Smurfs are sacrificed. She, No Name and Jaunty jump into an inter-dimensional portal, while Razamel gives chase and recaptures Jaunty. After more self doubt, No Name gains magical powers from within himself, turns the books good again, and defeats Razamel by banishing him into another dimension. Ron emerges from the dimensional door, reuniting with Ken and Papa. No Name, now giving himself the title of Magic Smurf, and the rest of the Smurfs return to Smurf Village to celebrate. In a mid-credits scene, Razamel is stuck in the unknown dimension with a
tardigrade, while Gargamel tells Joel that they have to capture the Smurfs. ==Voice cast==