Science Much of the series focuses on science, particularly physics. The four main male characters are employed at
Caltech and have science-related occupations, as do Bernadette and Amy. The characters frequently banter about scientific theories or news (notably around the
start of the show) and make science-related jokes. Science has also interfered with the characters' romantic lives. Leslie breaks up with Leonard when he sides with Sheldon in his support for
string theory rather than
loop quantum gravity. When Leonard joins Sheldon, Raj, and Howard on a three-month Arctic research trip, it separates Leonard and Penny at a time when their relationship is budding. When Bernadette takes an interest in Leonard's work, it makes both Penny and Howard envious and results in Howard confronting Leonard and Penny asking Sheldon to teach her physics. Sheldon and Amy also briefly end their relationship after an argument over which of their fields is superior. As the theme of the show revolves around science, many distinguished and high-profile scientists have appeared as guest stars on the show.
Astrophysicist and Nobel laureate
George Smoot had a
cameo appearance in the second season. Chemical engineer and Nobel laureate
Frances Arnold portrayed herself in the 12th season.
Theoretical physicist Brian Greene appeared in the fourth season, as well as astrophysicist, science popularizer, and
physics outreach specialist
Neil deGrasse Tyson, who also appeared in the twelfth season.
Cosmologist Stephen Hawking made a short guest appearance in a fifth-season episode; in the eighth season, Hawking video conferences with Sheldon and Leonard, and he makes another appearance in the 200th episode. In the fifth and sixth seasons, NASA astronaut
Michael J. Massimino played himself multiple times in the role of Howard's fellow astronaut. In the sixth season, NASA astronaut
Buzz Aldrin had a cameo appearance.
Bill Nye appeared in the seventh and twelfth seasons.
"Nerd" media '' actor
Wil Wheaton has a recurring role as a fictional version of himself on the show. The four main male characters are all avid fans of
nerd culture. Among their shared interests are
science fiction,
fantasy, comic books, and collecting memorabilia.
Star Trek in particular is referred to frequently, and Sheldon identifies strongly with the character of
Spock, so much so that when he is given a used napkin signed by
Leonard Nimoy as a Christmas gift from Penny, he is overwhelmed with excitement and gratitude ("I possess the DNA of Leonard Nimoy?!").
Star Trek: The Original Series cast members
William Shatner and
George Takei have made guest appearances, and Leonard Nimoy made a guest appearance as the voice of Sheldon's vintage Mr. Spock action figure.
Star Trek: The Next Generation cast members
Brent Spiner and
LeVar Burton have had guest appearances as themselves, while
Wil Wheaton has a recurring role as a
fictionalized version of himself. Leonard and Sheldon have had conversations in
Klingon. They are also fans of
Star Wars,
Battlestar Galactica, and
Doctor Who.
James Earl Jones,
Carrie Fisher and
Mark Hamill made guest appearances. In the episode "The Ornithophobia Diffusion", when there is a delay in watching
Star Wars on Blu-ray, Howard complains, "If we don't start soon,
George Lucas is going to change it again" (referring to Lucas' controversial alterations to the films). In "The Hot Troll Deviation",
Katee Sackhoff of
Battlestar Galactica appeared as Howard's fantasy dream girl. The characters have different tastes in franchises, with Sheldon praising
Firefly but disapproving of Leonard's enjoyment of
Babylon 5. With regard to fantasy, the four make frequent references to
The Lord of the Rings and
Harry Potter novels and movies. Additionally, Howard can speak
Sindarin, one of the two
Elvish languages from
The Lord of the Rings. Wednesday night is the group's designated "comic book night" because that is the day of the week when new comic books are released. The comic book store is run by fellow geek and recurring character Stuart. On a number of occasions, the group members have dressed up as pop culture characters, including
The Flash,
Aquaman,
Frodo Baggins,
Superman,
Batman,
Spock,
The Doctor,
Green Lantern, and
Thor. As a consequence of losing a bet to Stuart and Wil Wheaton, the group members are forced to visit the comic book store dressed as
Catwoman,
Wonder Woman,
Batgirl, and
Supergirl.
DC Comics announced that, to promote its comics, the company would sponsor Sheldon wearing Green Lantern T-shirts. Various games have been featured, as well as referred to, on the series (e.g.
World of Warcraft,
Halo,
Mario,
Donkey Kong, etc.), including fictional games like ''Mystic Warlords of Ka'a'' (which became a reality in 2011) and
Rock-paper-scissors-lizard-Spock.
Leonard and Penny's relationship One of the recurring plot lines is the relationship between Leonard and Penny. Leonard becomes attracted to Penny in the pilot episode, and his need to do favors for her is a frequent point of humor in the first season. Meanwhile, Penny dates a series of muscular, stereotypically "attractive," unintelligent, and insensitive jocks. Their first long-term relationship begins when Leonard returns from a three-month expedition to the
North Pole in the season 3 premiere. However, when Leonard tells Penny that he loves her, she realizes she cannot say it back, and they break up. Both Leonard and Penny go on to date other people, most notably with Leonard dating Raj's sister Priya for much of season 4. This relationship is jeopardized when Leonard mistakenly comes to believe that Raj has slept with Penny, and it ultimately ends when Priya sleeps with a former boyfriend in "
The Good Guy Fluctuation". Penny, who admits to missing Leonard in "
The Roommate Transmogrification", accepts his request to renew their relationship in "
The Beta Test Initiation". After Penny suggests having sex in "The Launch Acceleration", Leonard breaks the mood by proposing to her. Penny says "no" but does not break up with him. She stops a proposal a second time in "The Tangible Affection Proof". In the sixth-season episode, "The 43 Peculiarity", Penny finally tells Leonard that she loves him. Although they both feel jealousy when the other receives significant attention from the opposite sex, Penny is secure in their relationship, even when he leaves on a four-month expedition to the
North Sea in "The Bon Voyage Reaction". After he returns, the relationship blossoms over the seventh season. In the penultimate episode "The Gorilla Dissolution", Penny admits that they should marry and when Leonard realizes that she is serious, he proposes with a ring that he has been carrying for years. Leonard and Penny decide to elope to Las Vegas in the season 8 finale, but beforehand, wanting no secrets, Leonard admits to kissing another woman, Mandy Chow (
Melissa Tang) while on the expedition. Despite this, Leonard and Penny finally marry in the season 9 premiere and remain happy. By the Season 9 finale, Penny and Leonard decide to have a second wedding ceremony for their family and friends, to make up for eloping. In season 10, Sheldon moves into Penny's old apartment with Amy, allowing Penny and Leonard to finally live on their own as husband and wife. In season 12, Penny announces that she does not want to have any children and Leonard reluctantly supports her decision. Later, her old boyfriend Zack and his new wife want Leonard to be a surrogate father to their kid since Zack is infertile. Penny reluctantly agrees to let Leonard donate his sperm. However, when she tries to seduce Leonard despite knowing he has to be abstinent for a few days, her visiting father, Wyatt, points out to Penny that her own actions suggest she is more conflicted over having kids than she lets on, and she admits she feels bad about letting him and Leonard down if she never has children. He says that despite her flaws, parenthood is the best thing that ever happened to him, and he does not want her to miss out, but that he will support her no matter what she does. Leonard eventually changes his mind, not wanting a child in the world that he cannot raise. In the series finale, Penny is pregnant with Leonard's baby, and she has changed her mind about not wanting children.
Sheldon and Amy's relationship In the third-season finale, Raj and Howard sign Sheldon up for online dating to find a woman compatible with Sheldon, and they discover
neurobiologist Amy Farrah Fowler. Like Sheldon, she has a history of social ineptitude and participates in online dating only to fulfill an agreement with her mother. This spawns a story line in which Sheldon and Amy communicate daily while insisting to Leonard and Penny that they are not romantically involved. In "The Agreement Dissection", Sheldon and Amy talk in her apartment after a night of dancing, and she kisses him on the lips. Instead of getting annoyed, Sheldon says "fascinating" and later asks Amy to be his girlfriend in "The Flaming Spittoon Acquisition". The same night he draws up "The Relationship Agreement" to verify the ground rules of him as her boyfriend and vice versa (similar to his "Roommate Agreement" with Leonard). Amy agrees but later regrets not having had a lawyer read through it. In "The Launch Acceleration", Amy tries to use her "neurobiology bag of tricks" to increase the attraction between herself and Sheldon. Her efforts appear to be working because Sheldon is not happy, but he makes no attempt to stop her. In the fifth-season finale, "The Countdown Reflection", Sheldon takes Amy's hand as Howard is launched into space. In the sixth-season premiere, "The Date Night Variable", after a dinner in which Sheldon fails to live up to this expectation, Amy gives Sheldon an ultimatum that their relationship is over unless he tells her something from his heart. Amy accepts Sheldon's romantic speech even after learning that it is a line from the first
Spider-Man movie. In "The Cooper/Kripke Inversion", Sheldon states that he has been working on his discomfort about physical contact and admits that "it's a possibility" that he could one day have sex with Amy. Amy is revealed to have similar feelings in "The Love Spell Potential". Sheldon explains that he never thought about intimacy with anyone before Amy. "The Locomotive Manipulation" is the first episode in which Sheldon initiates a kiss with Amy. Although initially done in a fit of sarcasm, he discovers that he enjoys the feeling. Consequently, Sheldon slowly starts to open up over the rest of the season, and he starts a more intimate relationship with Amy. However, in the season finale, Sheldon leaves town temporarily to cope with several changes and Amy becomes distraught. However, 45 days into the trip, Sheldon gets mugged and calls for Leonard to drive him home, only to be confronted by Amy, who is upset over not being contacted by him in weeks. When Sheldon admits he did not call her because he was too embarrassed to admit that he could not make it on his own, Amy accepts that he is not perfect. In "The Prom Equivalency", Sheldon hides in his room to avoid going to a mock prom reenactment with her. In the resulting standoff, Amy is about to confess that she loves Sheldon, but he surprises her by saying that he loves her too. This prompts Amy to have a panic attack. In the season-eight finale, Sheldon and Amy get into a fight about commitment on their fifth anniversary. Amy tells Sheldon that she needs to think about the future of their relationship, unaware that Sheldon was about to propose to her. Season nine sees Sheldon harassing Amy about making up her mind until she breaks up with him. Both struggle with singlehood and trying to be friends for the next few weeks until they reunite in episode ten and have sex for the first time on Amy's birthday. In season ten, Amy's apartment is flooded, and she and Sheldon decide to move in together into Penny's apartment as part of a five-week experiment to determine compatibility with each other's living habits. It goes well and they decide to make the arrangement permanent. In the Season 11 premiere, Sheldon proposes to Amy, and she accepts. The two get married in the eleventh-season finale.
"Soft Kitty" The song "
Soft Kitty", which is sung by Sheldon, Penny, Leonard, Mary Cooper, and Amy during the series, is described by Sheldon as a song sung by his mother (Mary) when he was ill. Its repeated use in the series popularized the song. A scene showing the origin of the song in Sheldon's childhood is depicted in an episode of
Young Sheldon, which aired on February 1, 2018. It shows Sheldon's mother, Mary, singing the song to her son, who has the
flu.
Howard's mother In scenes set at Howard's home, he interacts with his rarely seen mother (voiced by
Carol Ann Susi until her death) by shouting from room to room in the house. She similarly interacts with other characters in this manner. She reflects the
Jewish mother stereotype in some ways, such as being overly controlling of Howard's adult life and sometimes trying to make him feel guilty about causing her trouble. She is dependent on Howard, as she requires him to help her with her wig and makeup in the morning. Howard, in turn, is attached to his mother to the point where she still cuts his meat for him, takes him to the dentist, does his laundry and "grounds" him when he returns home after briefly moving out. Until Howard's marriage to Bernadette in the fifth-season finale, Howard's former living situation led Leonard's psychiatrist mother to speculate that he may suffer from some type of pathology and Sheldon to refer to their relationship as
Oedipal. In season 8, Howard's mother dies in her sleep while in Florida, which devastates Howard and Stuart, who briefly lived with Mrs. Wolowitz.
Apartment building elevator In the apartment building where Sheldon, Leonard, and Penny (and later Amy) live, the elevator has been out of order throughout most of the series, forcing characters to have to use the stairs. Stairway conversations between the characters as they walk up the three flights to their apartments occur in almost every episode, often serving as a transition between longer scenes. The Season 3 episode, "The Staircase Implementation" reveals that the elevator was broken when Leonard was experimenting with rocket fuel. In the penultimate episode of the series, the elevator is returned to an operational state, causing Sheldon some angst, until he realizes that the fixed elevator reverted things to the "status quo".
Vanity cards Like most shows created by Chuck Lorre,
The Big Bang Theory ends by showing for one second a
vanity card written by Lorre after the credits, followed by the Warner Bros. Television closing logo. These cards are archived on Lorre's website. The series' final vanity card reads simply "The End". == Release ==