Ebola (2003-2014) DTRA has spent approximately $300 million on scientific R&D efforts since 2003, developing vaccines and therapeutic treatments against
viral hemorrhagic fever, including
Ebola. Starting in 2007, DTRA partnered with the
National Institute of Allergy and Infectious Diseases (NIAID) of the
United States Department of Health and Human Services and the
United States Army Medical Research Institute of Infectious Diseases (USAMRIID) to fund research on the drug now called
ZMapp, which has since been used on several patients. DTRA also funded and managed the research on the EZ1
assay used to detect and diagnose the presence of the
Ebola Zaire virus in humans. EZ1 was given
Emergency Use Authorization by the
Food and Drug Administration (FDA) in August 2014. DTRA first developed EZ1 as part of a 2011 "bio-preparedness initiative" for the
United States Department of Defense to prepare for a possible
Ebola outbreak. EZ1 was used to identify infected patients in
West Africa. The
Nunn-Lugar Cooperative Threat Reduction program provided for the DTRA to award a $4 million contract to
MRIGlobal to "configure, equip, deploy and staff two quick response mobile laboratory systems (MLS) to support the ongoing
Ebola outbreak in
West Africa." The labs were deployed to
Sierra Leone.
Transport Isolation System (2014) medical personnel tour the Transport Isolation System 23 January 2015, during a roll-out ceremony for the system on Scott AFB, Illinois. (USTRANSCOM photo) DTRA was the program manager for the Transport Isolation System (TIS), overseeing its design, testing, contracting, and production. The TIS is a sealed, self-contained patient containment unit that can be loaded into the
United States Air Force (USAF)
C-17 Globemaster or
C-130 Hercules cargo planes for
aeromedical evacuation. The TIS was designed for U.S. troops exposed to or infected with
Ebola while serving in
Operation United Assistance, but it can also be used to transport others exposed to or infected with a highly contagious disease. It can hold eight patients lying down, 12 sitting, or a combination of both. DTRA worked with the
Air Force Life Cycle Management Center (AFLCMC) and
United States Transportation Command (USTRANSCOM) on the TIS;
St. Louis-based Production Products was awarded a sole-source contract to produce 25 TIS units.
Syria's chemical weapons (2014) DTRA was one of the key
United States Department of Defense agencies that developed the
Field Deployable Hydrolysis System (FDHS) used to
destroy Syria's chemical weapons aboard the U.S.-flagged
container ship MV Cape Ray in the summer of 2014 after
Syria agreed to give up its chemical weapons stockpile under international pressure and in accordance with
United Nations Security Council Resolution 2118. DTRA partnered with the
United States Army Edgewood Chemical Biological Center (ECBC) to develop the FDHS and then modify it for ship-borne operations after
Syrian President
Bashar al-Assad agreed to turn over his country's poison gas arsenal and chemical weapon production equipment to the
Organisation for the Prohibition of Chemical Weapons (OPCW), but no country volunteered to host the destruction process. The remaining materials were then taken to Finland and Germany for final disposal. DTRA was awarded its third
Joint Meritorious Unit Award for successfully destroying Syria's declared chemical weapons.
Massive Ordnance Penetrator (to 2010) DTRA funded, managed, and tested the
Massive Ordnance Penetrator (MOP) bomb until February 2010, when the program was turned over to the USAF. DTRA developed the MOP to fulfill a long-standing Air Force requirement for a weapon that could destroy hard and deeply buried targets. The MOP is a 30,000-pound, 20.5-foot-long bomb dropped from
B-52 and
B-2 bombers at high altitude that can reportedly penetrate 200 feet of reinforced concrete. The MOP contains a 5,300-pound explosive charge, more than ten times the explosive power of its predecessor, the
BLU-109 "bunker buster."
Project MAXIMUS (to 2003) In 2003, a DTRA task force was identifying, collecting, and securing radiological material in Iraq as part of
Operation Iraqi Freedom, including almost two tons of
low-enriched uranium (LEU), several hundred tons of
yellowcake (a type of
uranium powder), and other radioactive sources. Code-named Project MAXIMUS, DTRA, and the
United States Department of Energy moved 1.77 metric tons of LEU and approximately 1,000 highly radioactive sources out of Iraq by the summer of 2004. DTRA task force members also secured the yellowcake in a bunker in
Tuwaitha, Iraq, which was turned over to the Iraqi Ministry of Science and Technology; the remaining 550 tons of yellowcake were sold in 2008 to
Cameco, a uranium producer in
Canada. == Awards and official recognition ==