Clarke had a lead role in the films
Letter to Brezhnev (1985),
The Dressmaker (1988) and
Strike It Rich (1990), and appeared in the
Pet Shop Boys' video for their 1987 single,"
Rent". She was the stand-in host for
Paula Yates on
Channel 4's
The Tube on several occasions. In 1989, she was cast as Queenie in the
BBC series
Making Out, set in a
Manchester electronics factory and written by
Debbie Horsfield. The show ran for three series. In 1991, she returned to presenting, this time on the late night
ITV show
The Good Sex Guide which gained audience figures of 13 million. She received a
Royal Television Society (RTS) Award for "Best Female Presenter" in 1994. A second series and third series followed. the last entitled
The Good Sex Guide Abroad. Clarke turned down an offer to take the series into a late night chat show format, the host eventually being
Toyah Willcox. In 1991, Clarke performed with
Half Man Half Biscuit on the single "No Regrets", a cover of the song, "
Non, je ne regrette rien", best known from the version recorded by
Édith Piaf. In the same year, she started in the film
Blonde Fist. Clarke portrayed Ronnie O'Dowd, a female boxer who follows her father into the world of 'pugilism' and rescues him from being 'on the skids' in New York to bring him back to Liverpool with her prize money. The film was written and directed by Clarke's brother Frank Clarke, who had previously written
Letter to Brezhnev. Following the success of
The Good Sex Guide, the ITV franchise holder
Carlton offered Clarke her own day-time show, and the resulting programme,
Swank, co-presented with fashion designer
David Emanuel, ran for two series. In 1994, Clarke tried a new venture,
stand-up comedy, and took her one-woman show
21st Century Scutt around the country - the tour included a stint at the
Edinburgh Film Festival and the
Royal Festival Hall on London's
South Bank. She was a regular guest on Channel 4's music show
The Word, including one occasion where she tricked presenter
Terry Christian into showing his testicles in a hidden camera set-up. Around this time, Clarke's partner was the artist
Jamie Reid (known for his work with the
Sex Pistols) and she was paid an undisclosed sum to pose nude while nine months pregnant with their daughter; the couple split up around 1997. The resulting pictures were a response to the then recent
Vanity Fair spread of actress
Demi Moore, in which she was shown nude while also nine months pregnant. The pictures of Clarke were published in the
Sunday People tabloid. She also published her own
vegetarian cookery book, ''Margi Clarke's Better than Sex Cookbook''. In 1994, Clarke worked with Welsh political band
Anhrefn for the single "Clutter from the Gutter". Her last role before taking a three-year sabbatical, following the death of her mother and birth of her daughter, was in the
BBC1 serial,
Soul Survivors co-starring
Ian McShane. She returned to acting in 1998, joining the
soap opera Coronation Street, playing
Jackie Dobbs. She left in 1999, and joined the cast of
Five soap opera Family Affairs, staying for just under a year, as well as guesting in an episode of the BBC's
Casualty. She also had roles in two films released in 2002,
Revengers Tragedy (adapted from the
17th century play), directed by
Alex Cox and
24 Hour Party People, the biopic of the
Factory/
Hacienda days in Manchester, which Clarke participated in during her 'Margox' days of the 1970s. In feature film
The Boys from County Clare (2003) she played the role of Dove. ==Since 2004==