List of EC numbers (EC 3)

EC 3.1.1: Carboxylic Ester Hydrolases • : carboxylesterase • : arylesterase • : triacylglycerol lipase • : phospholipase A2 • : lysophospholipase • : acetylesterase • : acetylcholinesterase • : cholinesterase • EC 3.1.1.9: deleted, a side reaction of cholinesterase • : tropinesterase • : pectinesterase • EC 3.1.1.12: deleted, identical with carboxylesterase • : sterol esterase • : chlorophyllase • : L-arabinonolactonase • EC 3.1.1.16: deleted, mixture of (muconolactone Δ-isomerase) and (3-oxoadipate enol-lactonase) • : gluconolactonase • EC 3.1.1.18: deleted, now included with gluconolactonase • : uronolactonase • : tannase • EC 3.1.1.21: deleted, now known to be catalysed by , carboxylesterase and , triacylglycerol lipase. • : hydroxybutyrate-dimer hydrolase • : acylglycerol lipase • : 3-oxoadipate enol-lactonase • : 1,4-lactonase • : galactolipase • : 4-pyridoxolactonase • : acylcarnitine hydrolase • : aminoacyl-tRNA hydrolase • : D-arabinonolactonase • : 6-phosphogluconolactonase • : phospholipase A1 • : 6-acetylglucose deacetylase • : lipoprotein lipase • : dihydrocoumarin hydrolase • : limonin-D-ring-lactonase • : steroid-lactonase • : triacetate-lactonase • : actinomycin lactonase • : orsellinate-depside hydrolase • : cephalosporin-C deacetylase • : chlorogenate hydrolase • : α-amino-acid esterase • : 4-methyloxaloacetate esterase • : carboxymethylenebutenolidase • : deoxylimonate A-ring-lactonase • : 1-alkyl-2-acetylglycerophosphocholine esterase • : fusarinine-C ornithinesterase • : sinapine esterase • : wax-ester hydrolase • : phorbol-diester hydrolase • : phosphatidylinositol deacylase • : sialate O-acetylesterase • : acetoxybutynylbithiophene deacetylase • : acetylsalicylate deacetylase • : methylumbelliferyl-acetate deacetylase • : 2-pyrone-4,6-dicarboxylate lactonase • : N-acetylgalactosaminoglycan deacetylase • : juvenile-hormone esterase • : bis(2-ethylhexyl)phthalate esterase • : protein-glutamate methylesterase • EC 3.1.1.62: Now listed as , N-acetyldiaminopimelate deacetylase • : 11-cis-retinyl-palmitate hydrolase • : retinoid isomerohydrolase • : L-rhamnono-1,4-lactonase • : 5-(3,4-diacetoxybut-1-ynyl)-2,2′-bithiophene deacetylase • : fatty-acyl-ethyl-ester synthase • : xylono-1,4-lactonase • EC 3.1.1.69: Now , N-acetylglucosaminylphosphatidylinositol deacetylase • : cetraxate benzylesterase • : acetylalkylglycerol acetylhydrolase • : acetylxylan esterase • : feruloyl esterase • : cutinase • : poly(3-hydroxybutyrate) depolymerase • : poly(3-hydroxyoctanoate) depolymerase • : acyloxyacyl hydrolase • : polyneuridine-aldehyde esterase • : hormone-sensitive lipase • : acetylajmaline esterase • : quorum-quenching N-acyl-homoserine lactonase • : pheophorbidase • : monoterpene ε-lactone hydrolase • : cocaine esterase • : pimelyl-(acyl-carrier protein) methyl ester esterase • : rhamnogalacturonan acetylesterase • : fumonisin B1 esterase • : pyrethroid hydrolase • : protein phosphatase methylesterase-1 • : all-trans-retinyl ester 13-cis isomerohydrolase • : 2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase • : 4-sulfomuconolactone hydrolase • : mycophenolic acid acyl-glucuronide esterase • : versiconal hemiacetal acetate esterase • : aclacinomycin methylesterase • : D-aminoacyl-tRNA deacylase • : methylated diphthine methylhydrolase • : (Wnt protein) O-palmitoleoyl-L-serine hydrolase|[Wnt protein] O-palmitoleoyl-L-serine hydrolase • : 6-deoxy-6-sulfogluconolactonase • : chlorophyllide a hydrolase • : poly(ethylene terephthalate) hydrolase • : mono(ethylene terephthalate) hydrolase • : teichoic acid D-alanine hydrolase • : 5-phospho-D-xylono-1,4-lactonase • : 3-O-acetylpapaveroxine carboxylesterase • : O-acetyl-ADP-ribose deacetylase • : apo-salmochelin esterase • : iron(III)-enterobactin esterase • : iron(III)-salmochelin esterase • : xylono-1,5-lactonase • : phosphatidylserine sn-1 acylhydrolase • : isoamyl acetate esterase • : ethyl acetate hydrolase • : methyl acetate hydrolase • : D-apionolactonase • : sn-1-specific diacylglycerol lipase • : (4-O-methyl)-D-glucuronate—lignin esterase • : phospholipid sn-1 acylhydrolase EC 3.1.2: Thioester Hydrolases • : acetyl-CoA hydrolase • : palmitoyl-CoA hydrolase • : succinyl-CoA hydrolase • : 3-hydroxyisobutyryl-CoA hydrolase • : hydroxymethylglutaryl-CoA hydrolase • : hydroxyacylglutathione hydrolase • : glutathione thiolesterase • EC 3.1.2.8: Now included with hydroxyacylglutathione hydrolase • EC 3.1.2.9: S-acetoacetylhydrolipoate hydrolase deleted • : formyl-CoA hydrolase • : acetoacetyl-CoA hydrolase • : S-formylglutathione hydrolase • : S-succinylglutathione hydrolase • : oleoyl-(acyl-carrier-protein) hydrolase|oleoyl-[acyl-carrier-protein] hydrolase • EC 3.1.2.15: covered by , ubiquitinyl hydrolase 1 • : citrate lyase deacetylase • : (S)-methylmalonyl-CoA hydrolase • : ADP-dependent short-chain-acyl-CoA hydrolase • : ADP-dependent medium-chain-acyl-CoA hydrolase • : acyl-CoA hydrolase • : dodecanoyl-(acyl-carrier-protein) hydrolase • : palmitoyl(protein) hydrolase|palmitoyl[protein] hydrolase • : 4-hydroxybenzoyl-CoA thioesterase • EC 3.1.2.24: transferred entry now , 2′-hydroxybiphenyl-2-sulfinate desulfinase. • : phenylacetyl-CoA hydrolase • EC 3.1.2.26: Now , bile acid CoA transferase • : choloyl-CoA hydrolase • : 1,4-dihydroxy-2-naphthoyl-CoA hydrolase • : fluoroacetyl-CoA thioesterase • : (3S)-malyl-CoA thioesterase • : dihydromonacolin L-(lovastatin nonaketide synthase) thioesterase|dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase • : 2-aminobenzoylacetyl-CoA thioesterase EC 3.1.3: Phosphoric Monoester Hydrolases • : alkaline phosphatase • : acid phosphatase • : phosphoserine phosphatase • : phosphatidate phosphatase • : 5′-nucleotidase • : 3′-nucleotidase • : 3′(2′),5′-bisphosphate nucleotidase • : 3-phytase • : glucose-6-phosphatase • : glucose-1-phosphatase • : fructose-bisphosphatase • : trehalose-phosphatase • EC 3.1.3.13: 5.4.2.11)), phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)|Recent studies have shown that this is a partial activity of , phosphoglycerate mutase (2,3-diphosphoglycerate-dependent) • : methylphosphothioglycerate phosphatase • : histidinol-phosphatase • : protein serine/threonine phosphatase • : (phosphorylase) phosphatase • : phosphoglycolate phosphatase • : glycerol-2-phosphatase • : phosphoglycerate phosphatase • : glycerol-1-phosphatase • : mannitol-1-phosphatase • : sugar-phosphatase • : sucrose-phosphatase • : inositol-phosphate phosphatase • : 4-phytase • : phosphatidylglycerophosphatase • : ADP-phosphoglycerate phosphatase • : N-acylneuraminate-9-phosphatase • EC 3.1.3.30: The activity may be that of an acid phosphatase • EC 3.1.3.31: The activity may be that of an acid phosphatase • : polynucleotide 3′-phosphatase • : polynucleotide 5′-phosphatase • : deoxynucleotide 3′-phosphatase • : thymidylate 5′-phosphatase • : phosphoinositide 5-phosphatase • : sedoheptulose-bisphosphatase • : 3-phosphoglycerate phosphatase • : streptomycin-6-phosphatase • : guanidinodeoxy-scyllo-inositol-4-phosphatase • : 4-nitrophenylphosphatase • : (glycogen-synthase-D) phosphatase|glycogen-synthase-D] phosphatase • : (pyruvate dehydrogenase (acetyl-transferring))-phosphatase|[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase • : (acetyl-CoA carboxylase)-phosphatase|[acetyl-CoA carboxylase]-phosphatase • : 3-deoxy-manno-octulosonate-8-phosphatase • : fructose-2,6-bisphosphate 2-phosphatase • : (hydroxymethylglutaryl-CoA reductase (NADPH))-phosphatase|[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase • : protein-tyrosine-phosphatase • : (pyruvate kinase)-phosphatase|[pyruvate kinase]-phosphatase • : sorbitol-6-phosphatase • : dolichyl-phosphatase • : (3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring))-phosphatase|[3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]-phosphatase • : (myosin-light-chain) phosphatase|[myosin-light-chain] phosphatase • : fructose-2,6-bisphosphate 6-phosphatase • : caldesmon-phosphatase • : inositol-polyphosphate 5-phosphatase • : inositol-1,4-bisphosphate 1-phosphatase • : sugar-terminal-phosphatase • : alkylacetylglycerophosphatase • : phosphoenolpyruvate phosphatase • EC 3.1.3.61: deleted, as its existence has not been established • : multiple inositol-polyphosphate phosphatase • : 2-carboxy-D-arabinitol-1-phosphatase • : phosphatidylinositol-3-phosphatase • EC 3.1.3.65: Now included with , phosphatidylinositol-3-phosphatase • : phosphatidylinositol-3,4-bisphosphate 4-phosphatase • : phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase • : 2-deoxyglucose-6-phosphatase • : glucosylglycerol 3-phosphatase • : mannosyl-3-phosphoglycerate phosphatase • : 2-phosphosulfolactate phosphatase • : 5-phytase • : adenosylcobalamin/α-ribazole phosphatase • : pyridoxal phosphatase • : phosphoethanolamine/phosphocholine phosphatase • : lipid-phosphate phosphatase • : acireductone synthase • : phosphatidylinositol-4,5-bisphosphate 4-phosphatase • : mannosylfructose-phosphate phosphatase • : 2,3-bisphosphoglycerate 3-phosphatase • EC 3.1.3.81: Transferred entry, now , diacylglycerol diphosphate phosphatase • : D-glycero-β-D-manno-heptose 1,7-bisphosphate 7-phosphatase • : D-glycero-α-D-manno-heptose 1,7-bisphosphate 7-phosphatase • : ADP-ribose 1′′-phosphate phosphatase • : glucosyl-3-phosphoglycerate phosphatase • : phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase • : 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase • : 5′′-phosphoribostamycin phosphatase EC 3.1.4: Phosphoric Diester Hydrolases • : phosphodiesterase I • : glycerophosphocholine phosphodiesterase • : lecithinase C • : phospholipase D • EC 3.1.4.5: Now , deoxyribonuclease I • EC 3.1.4.6: Now , deoxyribonuclease II • EC 3.1.4.7: Now , micrococcal nuclease • EC 3.1.4.8: Now , ribonuclease T1 • EC 3.1.4.9: Now , Serratia marcescens nuclease • EC 3.1.4.10: Now , phosphatidylinositol diacylglycerol-lyase • : phosphoinositide phospholipase C • : sphingomyelin phosphodiesterase • : serine-ethanolaminephosphate phosphodiesterase • : (acyl-carrier-protein) phosphodiesterase|[acyl-carrier-protein] phosphodiesterase • : transferred to EC 2.7.7.89, adenylyl-[glutamateammonia ligase] phosphorylase • : 2′,3′-cyclic-nucleotide 2′-phosphodiesterase • : 3′,5′-cyclic-nucleotide phosphodiesterase • EC 3.1.4.18: Now , spleen exonuclease • EC 3.1.4.19: Now , oligonucleotidase • EC 3.1.4.20: Now , exoribonuclease II • EC 3.1.4.21: Now , Aspergillus nuclease S1 • EC 3.1.4.22: Now , pancreatic ribonuclease • EC 3.1.4.23: Now , ribonuclease T2 • EC 3.1.4.24: deleted • EC 3.1.4.25: Now , exodeoxyribonuclease I • EC 3.1.4.26: deleted • EC 3.1.4.27: Now , exodeoxyribonuclease III • EC 3.1.4.28: Now , exodeoxyribonuclease (lambda-induced) • EC 3.1.4.29: deleted • EC 3.1.4.30: Now , deoxyribonuclease IV (phage-T4-induced) • EC 3.1.4.31: Now • EC 3.1.4.32: deleted • EC 3.1.4.33: deleted • EC 3.1.4.34: deleted • : 3′,5′-cyclic-GMP phosphodiesterase • EC 3.1.4.36: Now with • : 2′,3′-cyclic-nucleotide 3'-phosphodiesterase • : glycerophosphocholine cholinephosphodiesterase • : alkylglycerophosphoethanolamine phosphodiesterase • : CMP-N-acylneuraminate phosphodiesterase • : sphingomyelin phosphodiesterase D • : glycerol-1,2-cyclic-phosphate 2-phosphodiesterase • : glycerophosphoinositol inositolphosphodiesterase • : glycerophosphoinositol glycerophosphodiesterase • : N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase • : glycerophosphodiester phosphodiesterase • EC 3.1.4.47: Now , glycosylphosphatidylinositol diacylglycerol-lyase • : dolichylphosphate-glucose phosphodiesterase • : dolichylphosphate-mannose phosphodiesterase • : glycosylphosphatidylinositol phospholipase D • : glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase • : cyclic-guanylate-specific phosphodiesterase • : 3′,5′-cyclic-AMP phosphodiesterase • : N-acetylphosphatidylethanolamine-hydrolysing phospholipase D • : phosphoribosyl 1,2-cyclic phosphate phosphodiesterase • : 7,8-dihydroneopterin 2′,3′-cyclic phosphate phosphodiesterase • : phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase • : RNA 2′,3′-cyclic 3′-phosphodiesterase • : cyclic-di-AMP phosphodiesterase • : pApA phosphodiesterase • : cyclic 2,3-diphosphoglycerate hydrolase EC 3.1.5: Triphosphoric Monoester Hydrolases • : dGTPase EC 3.1.6: Sulfuric Ester Hydrolases • : arylsulfatase (type I) • : steryl-sulfatase • : glycosulfatase • : N-acetylgalactosamine-6-sulfatase • EC 3.1.6.5: deleted • : choline-sulfatase • : cellulose-polysulfatase • : cerebroside-sulfatase • : chondro-4-sulfatase • : chondro-6-sulfatase • : disulfoglucosamine-6-sulfatase • : N-acetylgalactosamine-6-sulfatase • : iduronate-2-sulfatase • : N-acetylglucosamine-6-sulfatase • : N-sulfoglucosamine-3-sulfatase • : monomethyl-sulfatase • : D-lactate-2-sulfatase • : Glucuronate-2-sulfatase • : (R)-specific secondary-alkylsulfatase (type III) • : S-sulfosulfanyl-L-cysteine sulfohydrolase • : linear primary-alkylsulfatase • : branched primary-alkylsulfatase EC 3.1.7: Diphosphoric Monoester Hydrolases • : prenyl-diphosphatase • : guanosine-3′,5′-bis(diphosphate) 3′-diphosphatase • : monoterpenyl-diphosphatase • EC 3.1.7.4: Now recognized as two enzymes , copal-8-ol diphosphate synthase and , sclareol synthase • : geranylgeranyl diphosphate diphosphatase • : farnesyl diphosphatase • EC 3.1.7.7: Now , (–)-drimenol synthase • EC 3.1.7.8: Now known to be a partial activity of , adenosine tuberculosinyltransferase. • EC 3.1.7.9: Now known to be a partial activity of , adenosine tuberculosinyltransferase • : (13E)-labda-7,13-dien-15-ol synthase • : geranyl diphosphate diphosphatase • : (+)-kolavelool synthase EC 3.1.8: Phosphoric Triester Hydrolases • : aryldialkylphosphatase • : diisopropyl-fluorophosphatase EC 3.1.11: Exodeoxyribonucleases Producing 5'-Phosphomonoesters • : exodeoxyribonuclease I • : exodeoxyribonuclease III • : exodeoxyribonuclease (lambda-induced) • : exodeoxyribonuclease (phage SP3-induced) • : exodeoxyribonuclease V • : exodeoxyribonuclease VII • EC 3.1.11.7: Now , adenosine-5′-diphospho-5′-[DNA] diphosphatase • EC 3.1.11.8: Now , guanosine-5′-diphospho-5′-[DNA] diphosphatase EC 3.1.13: Exoribonucleases Producing 5'-Phosphomonoesters • : exoribonuclease II • : exoribonuclease H • : oligonucleotidase • : poly(A)-specific ribonuclease • : ribonuclease D EC 3.1.14: Exoribonucleases Producing 3'-Phosphomonoesters • : yeast ribonuclease EC 3.1.15: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters • : venom exonuclease EC 3.1.16: Exonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters • : spleen exonuclease EC 3.1.21: Endodeoxyribonucleases Producing 5'-Phosphomonoesters • : deoxyribonuclease I • : deoxyribonuclease IV • : type I site-specific deoxyribonuclease • : type II site-specific deoxyribonuclease • : type III site-specific deoxyribonuclease • : CC-preferring endodeoxyribonuclease • : deoxyribonuclease V • : T4 deoxyribonuclease II • : T4 deoxyribonuclease IV • : crossover junction endodeoxyribonuclease EC 3.1.22: Endodeoxyribonucleases Producing 3'-Phosphomonoesters • : deoxyribonuclease II • : Aspergillus deoxyribonuclease K1 • EC 3.1.22.3: now • : crossover junction endodeoxyribonuclease • : deoxyribonuclease X EC 3.1.23: and EC 3.1.24 now EC 3.1.21.3, EC 3.1.21.4 and EC 3.1.21.5 Deleted sub-subclasses. EC 3.1.25: Site-Specific Endodeoxyribonucleases Specific for Altered Bases • : deoxyribonuclease (pyrimidine dimer) • EC 3.1.25.2: Now , DNA-(apurinic or apyrimidinic site) lyase EC 3.1.26: Endoribonucleases Producing 5'-Phosphomonoesters • : Physarum polycephalum ribonuclease • : ribonuclease α • : ribonuclease III • : ribonuclease H • : ribonuclease P • : ribonuclease IV • : ribonuclease P4 • : ribonuclease M5 • : ribonuclease (poly-(U)-specific) • : ribonuclease IX • : tRNase Z • : ribonuclease E • : retroviral ribonuclease H EC 3.1.27: Endoribonucleases Producing 3'-Phosphomonoesters • EC 3.1.27.1: Now , ribonuclease T2, since the primary reaction is that of a lyase • EC 3.1.27.2: Now , Bacillus subtilis ribonuclease, since the reaction catalysed is that of a lyase • EC 3.1.27.3: Now , ribonuclease T1, since the primary reaction is that of a lyase • EC 3.1.27.4: Now , ribonuclease U2, since the primary reaction is that of a lyase • EC 3.1.27.5: Now , pancreatic ribonuclease. • EC 3.1.27.6: Now , Enterobacter ribonuclease, since the primary reaction is that of a lyase • : ribonuclease F • : ribonuclease V • EC 3.1.27.9: Now , tRNA-intron lyase • EC 3.1.27.10: Now , ribotoxin, EC 3.1.30: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 5'-Phosphomonoesters • : Aspergillus nuclease S1 • : Serratia marcescens nuclease EC 3.1.31: Endoribonucleases Active with either Ribo- or Deoxyribonucleic Acids and Producing 3'-Phosphomonoesters • : micrococcal nuclease ==EC 3.2: Glycosylases==

===EC 3.2.1: Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds=== • : α-amylase • : β-amylase • : glucan 1,4-α-glucosidase • : cellulase • : deleted • : endo-1,3(4)-β-glucanase • : inulinase • : endo-1,4-β-xylanase • : deleted • : oligo-1,6-glucosidase • : dextranase • : Now included with , cyclomaltodextrinase • : Now included with , cyclomaltodextrinase • : chitinase • : polygalacturonase • : deleted • : lysozyme • : exo-α-sialidase • : deleted • : α-glucosidase • : β-glucosidase • : α-galactosidase • : β-galactosidase • : α-mannosidase • : β-mannosidase • : β-fructofuranosidase (invertase) • : deleted • : α,α-trehalase • : Now included with , β-N-acetylhexosaminidase • : Now included with , β-N-acetylhexosaminidase • : β-glucuronidase • : endo-1,3-β-xylanase • : amylo-α-1,6-glucosidase • : Now included with , hyaluronoglucosaminidase • : hyaluronoglucosaminidase • : hyaluronoglucuronidase • : xylan 1,4-β-xylosidase • : β-D-fucosidase • : glucan endo-1,3-β-D-glucosidase • : α-L-rhamnosidase • : pullulanase • : GDP-glucosidase • : β-L-rhamnosidase • : Now , endo-(13)-fucoidanase and , endo-(14)-fucoidanase • : glucosylceramidase • : galactosylceramidase • : Now known to be catalyzed by , α-galactosidase • : sucrose α-glucosidase • : α-N-acetylgalactosaminidase • : α-N-acetylglucosaminidase • : α-L-fucosidase • : β-N-acetylhexosaminidase • : β-N-acetylgalactosaminidase • : cyclomaltodextrinase • : non-reducing end α-L-arabinofuranosidase • : glucuronosyl-disulfoglucosamine glucuronidase • : isopullulanase • : glucan 1,3-β-glucosidase • : glucan endo-1,3-α-glucosidase • : glucan 1,4-α-maltotetraohydrolase • : mycodextranase • : glycosylceramidase • : 1,2-α-L-fucosidase • : 2,6-β-fructan 6-levanbiohydrolase • : levanase • : Deleted entry: The activity is covered by , α-L-rhamnosidase • : galacturan 1,4-α-galacturonidase • : isoamylase • : Now included with , pullulanase • : glucan 1,6-α-glucosidase • : glucan endo-1,2-β-glucosidase • : xylan 1,3-β-xylosidase • : licheninase • : glucan 1,4-β-glucosidase • : glucan endo-1,6-β-glucosidase • : L-iduronidase • : mannan 1,2-(1,3)-α-mannosidase • : mannan endo-1,4-β-mannosidase • : Now included with , non-reducing end α-L-arabinofuranosidase • : fructan β-fructosidase • : β-agarase • : exo-poly-α-digalacturonosidas • : κ-carrageenase • : glucan 1,3-α-glucosidase • : 6-phospho-β-galactosidase • : 6-phospho-β-glucosidase • : capsular-polysaccharide endo-1,3-α-galactosidase • : non-reducing end β-L-arabinopyranosidase • : arabinogalactan endo-β-1,4-galactanase • : Deleted, not sufficiently characterised. • : cellulose 1,4-β-cellobiosidase (non-reducing end) • : peptidoglycan β-N-acetylmuramidase • : α,α-phosphotrehalase • : glucan 1,6-α-isomaltosidase • : dextran 1,6-α-isomaltotriosidase • : mannosyl-glycoprotein endo-β-N-acetylglucosaminidase • : endo-α-N-acetylgalactosaminidase • : glucan 1,4-α-maltohexaosidase • : arabinan endo-1,5-α-L-arabinanase • : mannan 1,4-mannobiosidase • : mannan endo-1,6-α-mannosidase • : blood-group-substance endo-1,4-β-galactosidase • : keratan-sulfate endo-1,4-β-galactosidase • : steryl-β-glucosidase • : 3α(S)-strictosidine β-glucosidase • : mannosyl-oligosaccharide glucosidase • : protein-glucosylgalactosylhydroxylysine glucosidase • : lactase • : endogalactosaminidase • : identical to , endo-α-N-acetylgalactosaminidase • : 1,3-α-L-fucosidase • : 2-deoxyglucosidase • : mannosyl-oligosaccharide 1,2-α-mannosidase • : mannosyl-oligosaccharide 1,3-1,6-α-mannosidas • : branched-dextran exo-1,2-α-glucosidase • : glucan 1,4-α-maltotriohydrolase • : amygdalin β-glucosidase • : prunasin β-glucosidase • : vicianin β-glucosidase • : oligoxyloglucan β-glycosidase • : polymannuronate hydrolase • : maltose-6′-phosphate glucosidase • : endoglycosylceramidase • : 3-deoxy-2-octulosonidase • : raucaffricine β-glucosidase • : coniferin β-glucosidase • : 1,6-α-L-fucosidase • : glycyrrhizin hydrolase • : endo-α-sialidase • : glycoprotein endo-α-1,2-mannosidase • : xylan α-1,2-glucuronosidase • : chitosanase • : glucan 1,4-α-maltohydrolase • : difructose-anhydride synthase • : neopullulanase • : glucuronoarabinoxylan endo-1,4-β-xylanase • : mannan exo-1,2-1,6-α-mannosidase • EC 3.2.1.138: Now , anhydrosialidase • : α-glucuronidase • : lacto-N-biosidase • : 4-α-D-{(1→4)-α-D-glucano}trehalose trehalohydrolase • : limit dextrinase • : poly(ADP-ribose) glycohydrolase • : 3-deoxyoctulosonase • : galactan 1,3-β-galactosidase • : β-galactofuranosidase • : thioglucosidase • EC 3.2.1.148: 4.4.1.21)), S-ribosylhomocysteine lyase|The activity is most probably attributable to , S-ribosylhomocysteine lyase • : β-primeverosidase • : oligoxyloglucan reducing-end-specific cellobiohydrolase • : xyloglucan-specific endo-β-1,4-glucanase • : mannosylglycoprotein endo-β-mannosidase • : fructan β-(2,1)-fructosidase • : fructan β-(2,6)-fructosidase • : xyloglucan-specific endo-processive β-1,4-glucanase • : oligosaccharide reducing-end xylanase • : ι-carrageenase • : α-agarase • : α-neoagaro-oligosaccharide hydrolase • EC 3.2.1.160: identical to , xyloglucan-specific exo-β-1,4-glucanase • : β-apiosyl-β-glucosidase • : λ-carrageenase • : 1,6-α-D-mannosidase • : galactan endo-1,6-β-galactosidase • : exo-1,4-β-D-glucosaminidase • : heparanase • : baicalin-β-D-glucuronidase • : hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase • : protein O-GlcNAcas • : mannosylglycerate hydrolase • : rhamnogalacturonan hydrolase • : unsaturated rhamnogalacturonyl hydrolase • : rhamnogalacturonan galacturonohydrolase • : rhamnogalacturonan rhamnohydrolase • : β-D-glucopyranosyl abscisate β-glucosidase • : cellulose 1,4-β-cellobiosidase (reducing end) • : α-D-xyloside xylohydrolase • : β-porphyranase • : gellan tetrasaccharide unsaturated glucuronyl hydrolase • : unsaturated chondroitin disaccharide hydrolase • : galactan endo-β-1,3-galactanase • : 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside β-D-glucosidase • : UDP-N-acetylglucosamine 2-epimerase (hydrolysing) • : UDP-N,N′-diacetylbacillosamine 2-epimerase (hydrolysing) • : non-reducing end β-L-arabinofuranosidase • : protodioscin 26-O-β-D-glucosidase • : (Ara-f)3-Hyp β-L-arabinobiosidase • : avenacosidase * • : dioscin glycosidase (diosgenin-forming) • : dioscin glycosidase (3-O-β-D-Glc-diosgenin-forming) • : ginsenosidase type III • : ginsenoside Rb1 β-glucosidase • : ginsenosidase type I • : ginsenosidase type IV • : 20-O-multi-glycoside ginsenosidase • : limit dextrin α-1,6-maltotetraose-hydrolase • : β-1,2-mannosidase • : α-mannan endo-1,2-α-mannanase • : sulfoquinovosidase • : exo-chitinase (non-reducing end) • : exo-chitinase (reducing end) • : endo-chitodextinase • : carboxymethylcellulase • : 1,3-α-isomaltosidase • : isomaltose glucohydrolase • : oleuropein β-glucosidase • : mannosyl-oligosaccharide α-1,3-glucosidase • : glucosylglycerate hydrolase • : endoplasmic reticulum Man9GlcNAc2 1,2-α-mannosidase • : endoplasmic reticulum Man8GlcNAc2 1,2-α-mannosidase • : endo-(1→3)-fucoidanase • : endo-(1→4)-fucoidanase • : galactan exo-1,6-β-galactobiohydrolase (non-reducing end) • : exo β-1,2-glucooligosaccharide sophorohydrolase (non-reducing end) EC 3.2.2: Hydrolysing N-Glycosyl Compounds • : purine nucleosidase • : inosine nucleosidase • : uridine nucleosidase • : AMP nucleosidase • : NAD+ glycohydrolase • : ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase • : adenosine nucleosidase • : ribosylpyrimidine nucleosidase • : adenosylhomocysteine nucleosidase • : pyrimidine-5′-nucleotide nucleosidase • : β-aspartyl-N-acetylglucosaminidase • : inosinate nucleosidase • : 1-methyladenosine nucleosidase • : NMN nucleosidase • : DNA-deoxyinosine glycosylase • : methylthioadenosine nucleosidase • : deoxyribodipyrimidine endonucleosidase • EC 3.2.2.18: Now included with , peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase • : ADP-ribosylarginine hydrolase • : DNA-3-methyladenine glycosylase I • : DNA-3-methyladenine glycosylase II, MAG1 • : rRNA 'N-glycosylase • : DNA-formamidopyrimidine glycosylase • : ADP-ribosyl-(dinitrogen reductase) hydrolase| ADP-ribosyl-[dinitrogen reductase] hydrolase • : N-methyl nucleosidase • : futalosine hydrolase • : uracil-DNA glycosylase • : double-stranded uracil-DNA glycosylase • : thymine-DNA glycosylase • : aminodeoxyfutalosine nucleosidase • : adenine glycosylase EC 3.2.3: Hydrolysing S-Glycosyl Compounds Deleted sub-subclass ==EC 3.3: Acting on Ether Bonds==

EC 3.3.1: Thioether and trialkylsulfonium hydrolases • : adenosylhomocysteinase • : S-adenosyl-L-methionine hydrolase (L-homoserine-forming) • EC 3.3.1.3: 4.4.1.21)), S-ribosylhomocysteine lyase|The activity is most probably attributable to , S-ribosylhomocysteine lyase EC 3.3.2: Ether Hydrolases • : isochorismatase • : alkenylglycerophosphocholine hydrolase • EC 3.3.2.3: Now known to comprise two enzymes, microsomal epoxide hydrolase () and soluble epoxide hydrolase () • : trans-epoxysuccinate hydrolase • EC 3.3.2.5: Now included in , lysoplasmalogenase • : leukotriene-A4 hydrolase • : hepoxilin-epoxide hydrolase • : limonene-1,2-epoxide hydrolase • : microsomal epoxide hydrolase • : soluble epoxide hydrolase • : cholesterol-5,6-oxide hydrolase • : oxepin-CoA hydrolase • : chorismatase • : 2,4-dinitroanisole O-demethylase • : trans-2,3-dihydro-3-hydroxyanthranilic acid synthase ==EC 3.4: Acting on peptide bonds – Peptidase==

EC 3.4.1 α-amino acyl peptide hydrolases (discontinued) • EC 3.4.1.1: Now , leucyl aminopeptidase • EC 3.4.1.2: Now , membrane alanyl aminopeptidase • EC 3.4.1.3: Now , tripeptide aminopeptidase • EC 3.4.1.4: Now , prolyl aminopeptidase EC 3.4.2 Peptidyl amino acid hydrolases (discontinued) • EC 3.4.2.1: Now , carboxypeptidase A • EC 3.4.2.2: Now , carboxypeptidase B • EC 3.4.2.3: Now , Gly-Xaa carboxypeptidase EC 3.4.3: Dipeptide hydrolases (deleted sub-subclass) • EC 3.4.3.1: Now , cytosol nonspecific dipeptidase • EC 3.4.3.2: Now , cytosol nonspecific dipeptidase • EC 3.4.3.3: Now , Xaa-His dipeptidase • EC 3.4.3.4: Now , Xaa-methyl-His dipeptidase • EC 3.4.3.5: Now , membrane alanyl aminopeptidase • EC 3.4.3.6: Now , cytosol nonspecific dipeptidase • EC 3.4.3.7: Now , Xaa-Pro dipeptidase EC 3.4.4 Peptidyl Peptide Hydrolases (discontinued) • EC 3.4.4.1: Now , pepsin A • EC 3.4.4.2: Now , pepsin B • EC 3.4.4.3: Now , chymosin • EC 3.4.4.4: Now , trypsin • EC 3.4.4.5: Now , chymotrypsin • EC 3.4.4.6: Now , chymotrypsin • EC 3.4.4.7: Now covered by , pancreatic elastase and , leukocyte elastase • EC 3.4.4.8: Now , enteropeptidase • EC 3.4.4.9: Now , dipeptidyl-peptidase I • EC 3.4.4.10: Now , papain • EC 3.4.4.11: Now , chymopapain • EC 3.4.4.12: Now , ficain • EC 3.4.4.13: Now , thrombin • EC 3.4.4.14: Now , plasmin • EC 3.4.4.15: Now , renin • EC 3.4.4.16: Now covered by the microbial serine proteinases (subtilisin), (oryzin), (endopeptidase K), (thermomycolin), (thermitase) and (endopeptidase So) • EC 3.4.4.17: Now covered by the microbial aspartic proteinases (penicillopepsin), (rhizopuspepsin), (endothiapepsin), (mucorpepsin), (candidapepsin), (saccharopepsin), (rhodotorulapepsin), (physarolisin), (acrocylindropepsin), (polyporopepsin) and (pycnoporopepsin) • EC 3.4.4.18: Now , streptopain • EC 3.4.4.19: Now , microbial collagenase • EC 3.4.4.20: Now , clostripain • EC 3.4.4.21: Now (plasma kallikrein) and (tissue kallikrein) • EC 3.4.4.22: Now , gastricsin • EC 3.4.4.23: Now , cathepsin D • EC 3.4.4.24: Now covered by (stem bromelain) and (fruit bromelain) • EC 3.4.4.25: deleted ===EC 3.4.11 Aminopeptidases=== • : leucyl aminopeptidase • : membrane alanyl aminopeptidase • : cystinyl aminopeptidase • : tripeptide aminopeptidase • : prolyl aminopeptidase • : aminopeptidase B • : glutamyl aminopeptidase • EC 3.4.11.8: Now EC 3.4.19.3, pyroglutamyl-peptidase I • : Xaa-Pro aminopeptidase • : bacterial leucyl aminopeptidase • EC 3.4.11.11: Deleted • EC 3.4.11.12: Deleted • : Clostridial aminopeptidase • : cytosol alanyl aminopeptidase • : aminopeptidase Y • : Xaa-Trp aminopeptidase • : tryptophanyl aminopeptidase • : methionyl aminopeptidase • : D-stereospecific aminopeptidase • : aminopeptidase Ey • : aspartyl aminopeptidase • : aminopeptidase I • : PepB aminopeptidase • : aminopeptidase S • : β-peptidyl aminopeptidase • : intermediate cleaving peptidase 55 EC 3.4.12 Peptidylamino-acid hydrolases or acylamino-acid hydrolases (deleted sub-subclass) • EC 3.4.12.1: Now (carboxypeptidase C) and (carboxypeptidase D) • EC 3.4.12.2: Now , carboxypeptidase A • EC 3.4.12.3: Now , carboxypeptidase B • EC 3.4.12.4: Now , lysosomal Pro-Xaa carboxypeptidase • EC 3.4.12.5: Now , N-acetylmuramoyl-L-alanine amidase • EC 3.4.12.6: Now , muramoyl-pentapeptidase carboxypeptidase • EC 3.4.12.7: Now , lysine carboxypeptidase • EC 3.4.12.8: Now , Gly-Xaa carboxypeptidase • EC 3.4.12.9: aspartate carboxypeptidase • EC 3.4.12.10: Now , γ-glutamyl hydrolase • EC 3.4.12.11: Now , alanine carboxypeptidase • EC 3.4.12.12: Now (carboxypeptidase C) and (carboxypeptidase D) • EC 3.4.12.13: γ-glutamylglutamate carboxypeptidase EC 3.4.13 Dipeptidases • EC 3.4.13.1: Now , cytosol nonspecific dipeptidase • EC 3.4.13.2: Now , cytosol nonspecific dipeptidase • EC 3.4.13.3: The activity is covered by , cytosol nonspecific dipeptidase and , β-Ala-His dipeptidase • : Xaa-Arg dipeptidase • : Xaa-methyl-His dipeptidase • EC 3.4.13.6: Now , membrane alanyl aminopeptidase • : Glu-Glu dipeptidase • EC 3.4.13.8: Now , cytosol nonspecific dipeptidase • : Xaa-Pro dipeptidase • EC 3.4.13.10: Now , β-aspartyl-peptidase • EC 3.4.13.11: Now , membrane dipeptidase • : Met-Xaa dipeptidase • EC 3.4.13.13: Now , Xaa-His dipeptidase • EC 3.4.13.14: Deleted • EC 3.4.13.15: Now , cytosol nonspecific dipeptidase • : Deleted • : non-stereospecific dipeptidase • : cytosol nonspecific dipeptidase • : membrane dipeptidase • : β-Ala-His dipeptidase • : dipeptidase E • : D-Ala-D-Ala dipeptidase • : cysteinylglycine-S-conjugate dipeptidase ===EC 3.4.14 Dipeptidyl peptidases and tripeptidyl peptidases=== • : dipeptidyl-peptidase I • : dipeptidyl-peptidase II • EC 3.4.14.3: Now , acylaminoacyl-peptidase • : dipeptidyl-peptidase III • : dipeptidyl-peptidase IV • : dipeptidyl-dipeptidase • EC 3.4.14.7: Deleted • EC 3.4.14.8: Now , tripeptidyl-peptidase II • : tripeptidyl-peptidase I • : tripeptidyl-peptidase II • : Xaa-Pro dipeptidyl-peptidase • : Xaa-Xaa-Pro tripeptidyl-peptidase • : γ-D-glutamyl-Llysine dipeptidyl-peptidase • : (mycofactocin precursor peptide) peptidase|[mycofactocin precursor peptide] peptidase ===EC 3.4.15 Peptidyl dipeptidases=== • : peptidyl-dipeptidase A • EC 3.4.15.2: Now , peptidyl-glycinamidase • EC 3.4.15.3: Now , peptidyl-dipeptidase Dcp • : Peptidyl-dipeptidase B • : Peptidyl-dipeptidase Dcp • : cyanophycinase ===EC 3.4.16 Serine type carboxypeptidases=== • EC 3.4.16.1: Transferred entry: serine carboxypeptidase. Now , carboxypeptidase D • : lysosomal Pro-Xaa carboxypeptidase • EC 3.4.16.3: Now included with , carboxypeptidase C • : serine-type D-Ala-D-Ala carboxypeptidase • : carboxypeptidase C • : carboxypeptidase D ===EC 3.4.17 Metallocarboxypeptidases=== • : carboxypeptidase A • : carboxypeptidase B • : lysine carboxypeptidase • : Gly-Xaa carboxypeptidase • EC 3.4.17.5: Deleted • : alanine carboxypeptidase • EC 3.4.17.7: Now , N-acetylmuramoyl-L-alanine amidase • : muramoylpentapeptide carboxypeptidase • EC 3.4.17.9: Now included with , Gly-Xaa carboxypeptidase • : carboxypeptidase E • : glutamate carboxypeptidase • : carboxypeptidase M • : Muramoyltetrapeptide carboxypeptidase • : zinc D-Ala-D-Ala carboxypeptidase • : carboxypeptidase A2 • : membrane Pro-Xaa carboxypeptidase • : tubulinyl-Tyr carboxypeptidase • : carboxypeptidase T • : Carboxypeptidase Taq • : carboxypeptidase U • : Glutamate carboxypeptidase II • : metallocarboxypeptidase D • : angiotensin-converting enzyme 2 • : tubulin-glutamate carboxypeptidase ===EC 3.4.18 Cysteine type carboxypeptidases=== • : cathepsin X ===EC 3.4.19 Omega peptidases=== • : acylaminoacyl-peptidase • : peptidyl-glycinamidase • : pyroglutamyl-peptidase I • EC 3.4.19.4: Deleted • : β-aspartyl-peptidase • : pyroglutamyl-peptidase II • : N-formylmethionyl-peptidase • EC 3.4.19.8: now , glutamate carboxypeptidase II • : folate γ-glutamyl hydrolase • EC 3.4.19.10: Now , N-acetylmuramoyl-L-alanine amidase • : γ-Dglutamyl-meso-diaminopimelate peptidase • : ubiquitinyl hydrolase 1 • : glutathione γ-glutamate hydrolase • : leukotriene-C4 hydrolase • : desampylase • : glucosinolate γ-glutamyl hydrolase ===EC 3.4.21: Serine proteases=== • : chymotrypsin • : chymotrypsin C • : metridin • : trypsin • : thrombin • : coagulation factor Xa • : plasmin • EC 3.4.21.8: Now (plasma kallikrein) and (tissue kallikrein) • : enteropeptidase • : acrosin • EC 3.4.21.11: Now , leukocyte elastase • : α-lytic endopeptidase • EC 3.4.21.13: Now , carboxypeptidase D • EC 3.4.21.14: now , endopeptidase So • EC 3.4.21.15: Now , oryzin • EC 3.4.21.16: Deleted • EC 3.4.21.17: Deleted • EC 3.4.21.18: Deleted • : glutamyl endopeptidase • : cathepsin G • : coagulation factor VIIa • : coagulation factor IXa • EC 3.4.21.23: Deleted • EC 3.4.21.24: Deleted • : cucumisin • : prolyl oligopeptidase • : coagulation factor XIa • EC 3.4.21.28: Now , venombin A • EC 3.4.21.29: Now , venombin A • EC 3.4.21.30: Now , venombin A • EC 3.4.21.31: Now , u-plasminogen activator • : brachyurin • EC 3.4.21.33: Deleted • : plasma kallikrein • : tissue kallikrein • : pancreatic elastase • : leukocyte elastase • : coagulation factor XIIa • : chymase • EC 3.4.21.40: Deleted • : Complement subcomponent C1r • : complement subcomponent C1s • : classical-complement-pathway C3/C5 convertase • EC 3.4.21.44: Now , classical-complement-pathway C3/C5 convertase • : complement factor I • : complement factor D • : alternative-complement-pathway C3/C5 convertase • : cerevisin • : hypodermin C • : lysyl endopeptidase • EC 3.4.21.51: Deleted • EC 3.4.21.52: Deleted • : edopeptidase La • : γ-renin • : venombin AB • EC 3.4.21.56: Now considered to be , cucumisin • : leucyl endopeptidase • EC 3.4.21.58: Deleted • : tryptase • : scutelarin • : kexin • : subtilisin • : oryzin • : endopeptidase K • : thermomycolin • : thermitase • : endopeptidase So • : t-plasminogen activator • : protein C (activated) • : pancreatic endopeptidase E • : pancreatic elastase II • : IgA-specific serine endopeptidase • : u-plasminogen activator • : venombin A • : furin • : myeloblastin • : semenogelase • : granzyme A • : granzyme B • : streptogrisin A • : streptogrisin B • : glutamyl endopeptidase II • : oligopeptidase B • : limulus clotting factor C • : limulus clotting factor B • : limulus clotting enzyme • EC 3.4.21.87: Now , omptin • : repressor LexA • : signal peptidase I • : togavirin • : flavivirin • : endopeptidase Clp • : proprotein convertase 1 • : proprotein convertase 2 • : snake venom factor V activator • : lactocepin • : assemblin • : hepacivirin • : spermosin • : sedolisin • : xanthomonalisin • : C-terminal processing peptidase • : physarolisin • : mannan-binding lectin-associated serine protease-2 • : rhomboid protease • : hepsin • : peptidase Do • : HtrA2 peptidase • : matriptase • : C5a peptidase • : aqualysin 1 • : site-1 protease • : pestivirus NS3 polyprotein peptidase • : equine arterivirus serine peptidase • : infectious pancreatic necrosis birnavirus Vp4 peptidase • : SpoIVB peptidase • : stratum corneum chymotryptic enzyme • : kallikrein 8 • : kallikrein 13 • : oviductin • : Lys-Lys/Arg-Xaa endopeptidase ===EC 3.4.22 Cysteine proteases=== • : cathepsin B • : papain • : ficain • EC 3.4.22.4: Now (stem bromelain) and (fruit bromelain) • EC 3.4.22.5: Now (stem bromelain) and (fruit bromelain) • : chymopapain • : asclepain • : clostripain • EC 3.4.22.9: Now , cerevisin • : streptopain • EC 3.4.22.11: Now , insulysin • EC 3.4.22.12: Now , γ-glutamyl hydrolase • EC 3.4.22.13: Deleted • : actinidain • : cathepsin L • : cathepsin H • EC 3.4.22.17: Now , calpain-2 • EC 3.4.22.18: Now , prolyl oligopeptidase • EC 3.4.22.19: Now , thimet oligopeptidase • EC 3.4.22.20: Deleted • EC 3.4.22.21: Now , proteasome endopeptidase complex • EC 3.4.22.22: Now , saccharolysin • EC 3.4.22.23: Now , kexin • : Cathepsin T • : Glycyl endopeptidase • : Cancer procoagulant • : cathepsin S • : picornain 3C • : picornain 2A • : Caricain • : Ananain • : Stem bromelain • : Fruit bromelain • : Legumain • : Histolysain • : caspase-1 • : Gingipain R • : Cathepsin K • : adenain • : bleomycin hydrolase • : cathepsin F • : cathepsin O • : cathepsin V • : nuclear-inclusion-a endopeptidase • : helper-component proteinase • : L-peptidase • : gingipain K • : staphopain • : separase • : V-cath endopeptidase • : cruzipain • : calpain-1 • : calpain-2 • : calpain-3 • : caspase-2 • : caspase-3 • : caspase-4 • : caspase-5 • : caspase-6 • : caspase-7 • : caspase-8 • : caspase-9 • : caspase-10 • : caspase-11 • : peptidase 1 (mite) • : calicivirin • : zingipain • : Ulp1 peptidase • : SARS coronavirus main proteinase • : sortase A • : sortase B ===EC 3.4.23 Aspartic endopeptidases=== • : pepsin A • : pepsin B • : gastricsin • : chymosin • : cathepsin D • EC 3.4.23.6: Now , pycnoporopepsin • EC 3.4.23.7: Now , penicillopepsin • EC 3.4.23.8: Now , saccharopepsin • EC 3.4.23.9: Now , rhizopuspepsin • EC 3.4.23.10: Now , endothiapepsin • EC 3.4.23.11: Deleted entry • : nepenthesin • EC 3.4.23.13: Deleted • EC 3.4.23.14: Deleted • : renin • : HIV-1 retropepsin • : pro-opiomelanocortin converting enzyme • : aspergillopepsin I • : aspergillopepsin II • : penicillopepsin • : rhizopuspepsin • : endothiapepsin • : mucorpepsin • : candidapepsin • : saccharopepsin • : rhodotorulapepsin • EC 3.4.23.27: Now , physarolisin • : acrocylindropepsin • : polyporopepsin • : pycnoporopepsin • : scytalidopepsin A • : scytalidopepsin B • EC 3.4.23.33: Now , xanthomonalisin • : cathepsin E • : barrierpepsin • : signal peptidase II • EC 3.4.23.37: Now , pseudomonalisin • : plasmepsin I • : plasmepsin II • : phytepsin • : yapsin 1 • : thermopsin • : prepilin peptidase • : nodavirus endopeptidase • : memapsin 1 • : memapsin 2 • : HIV-2 retropepsin • : plasminogen activator Pla • : omptin • : human endogenous retrovirus K endopeptidase • : HycI peptidase • : preflagellin peptidase ===EC 3.4.24: Metallopeptidases=== • : atrolysin A • : Deleted entry: Sepia proteinase • : microbial collagenase • : now serralysin • EC 3.4.24.5: Deleted entry: lens neutral proteinase. Now included with (calpain-2) and (proteasome endopeptidase complex) • : leucolysin • : interstitial collagenase • EC 3.4.24.8: Transferred entry: Achromobacter iophagus collagenase. Now , microbial collagenase • EC 3.4.24.9: Deleted entry: Trichophyton schoenleinii collagenase • EC 3.4.24.10: Deleted entry: Trichophyton mentagrophytes keratinase • : neprilysin • : envelysin • : IgA-specific metalloendopeptidase • : procollagen N-endopeptidase • : thimet oligopeptidase • : neurolysin • : stromelysin 1 • : meprin A • : procollagen C-endopeptidase • : peptidyl-Lys metalloendopeptidase • : astacin • : stromelysin 2 • : matrilysin • : gelatinase a • : vibriolysin • : pseudolysin • : thermolysin • : bacillolysin • : aureolysin • : coccolysin • : mycolysin • : β-lytic metalloendopeptidase • : peptidyl-Asp metalloendopeptidase • : neutrophil collagenase • : gelatinase B • : leishmanolysin • : saccharolysin • : gametolysin • : deuterolysin • : serralysin • : atrolysin B • : atrolysin C • : atroxase • : atrolysin E • : atrolysin F • : adamalysin • : horrilysin • : ruberlysin • : bothropasin • : bothrolysin • : ophiolysin • : trimerelysin I • : trimerelysin II • : mucrolysin • : pitrilysin • : insulysin • : O-sialoglycoprotein endopeptidase • : russellysin • : mitochondrial intermediate peptidase • : dactylysin • : nardilysin • : magnolysin • : meprin B • : mitochondrial processing peptidase • : macrophage elastase • : choriolysin L • : choriolysin H • : tentoxilysin • : bontoxilysin • : oligopeptidase A • : endothelin-converting enzyme 1 • : fibrolase • : jararhagin • : fragilysin • : lysostaphin • : flavastacin • : snapalysin • : gpr endopeptidase • : pappalysin-1 • : membrane-type matrix metalloproteinase-1 • : ADAM10 endopeptidase • : ADAMTS-4 endopeptidase • : anthrax lethal factor endopeptidase • : Ste24 endopeptidase • : S2P endopeptidase • : ADAM 17 endopeptidase • : ADAMTS13 endopeptidase ===EC 3.4.25 Threonine endopeptidases=== • : proteasome endopeptidase complex • : HslU—HslV peptidase • EC 3.4.99.7: Deleted entry: euphorbain • EC 3.4.99.8: Deleted entry: Gliocladium proteinase • EC 3.4.99.9: Deleted entry: hurain. Now considered to be , cucumisin • EC 3.4.99.10: Transferred entry: insulinase. Now , insulysin • EC 3.4.99.11: Deleted entry: Streptomyces alkalophilic keratinase • EC 3.4.99.12: Deleted entry: Trichophyton mentagrophytes keratinase • EC 3.4.99.13: Transferred entry: β-lytic proteinase (Mycobacterium sorangium). Now , β-lytic metalloendopeptidase • EC 3.4.99.14: Deleted entry: mexicanain • EC 3.4.99.15: Deleted entry: Paecilomyces proteinase • EC 3.4.99.16: Deleted entry: Penicillium notatum extracellular proteinase • EC 3.4.99.17: Deleted entry: peptidoglycan endopeptidase • EC 3.4.99.18: Deleted entry: pinguinain • EC 3.4.99.19: Transferred entry: renin. Now , renin • EC 3.4.99.20: Deleted entry: scopulariopsis proteinase • EC 3.4.99.21: Deleted entry: solanain. Now considered , cucumisin • EC 3.4.99.22: Transferred entry: staphylokinase. , aureolysin • EC 3.4.99.23: Deleted entry: tabernamontanain. Now considered EC 3.4.21.25, cucumisin • EC 3.4.99.24: Deleted entry: Tenebrio α-proteinase • EC 3.4.99.25: Transferred entry: trametes acid proteinase. , rhizopuspepsin • EC 3.4.99.26: Transferred entry: urokinase. Now , t-plasminogen activator • EC 3.4.99.27: Deleted entry: Echis carinatus prothrombin-activating proteinase • EC 3.4.99.28: Transferred entry: Oxyuranus scutellatus prothrombin-activating proteinase. , scutelarin • EC 3.4.99.29: Deleted entry: Myxobacter AL-1 proteinase I • EC 3.4.99.30: Transferred entry: Myxobacter AL-1 proteinase II. , peptidyl-Lys metalloendopeptidase • EC 3.4.99.31: Transferred entry: tissue endopeptidase degrading collagenase synthetic substrate. , thimet oligopeptidase • EC 3.4.99.32: Transferred entry: Armillaria mellea neutral proteinase. Now , peptidyl-Lys metalloendopeptidase • EC 3.4.99.33: Deleted entry: cathepsin R • EC 3.4.99.34: Deleted entry: mytilidase • EC 3.4.99.35: Transferred entry: premurein-leader peptidase. Now , signal peptidase II • EC 3.4.99.36: Transferred entry: leader peptidase. Now , signal peptidase I • EC 3.4.99.37: Deleted entry: RecA peptidase • EC 3.4.99.38: Transferred entry: pro-opiomelanotropin-converting proteinase. Now , pro-opiomelanocortin converting enzyme • EC 3.4.99.39: Deleted entry: pseudomurein endopeptidase • EC 3.4.99.40: Deleted entry: pro-gonadoliberin proteinase • EC 3.4.99.41: Transferred entry: mitochondrial processing peptidase. Now , mitochondrial processing peptidase • EC 3.4.99.42: Deleted entry: leucyllysine endopeptidase • EC 3.4.99.43: Transferred entry: thermopsin. Npw , thermopsin • EC 3.4.99.44: Transferred entry: pitrilysin. Now , pitrilysin • EC 3.4.99.45: Transferred entry: insulinase. Now , insulysin • EC 3.4.99.46: Transferred entry: multicatalytic endopeptidase complex. Now , proteasome endopeptidase complex ==EC 3.5: Acting on carbon-nitrogen bonds, other than peptide bonds==

3.5.1: In linear amides • : asparaginase • : glutaminase • : ω-amidase • : amidase • : urease • : β-ureidopropionase • : ureidosuccinase • : formylaspartate deformylase • : arylformamidase • : formyltetrahydrofolate deformylase • : penicillin amidase • : biotinidase • : aryl-acylamidase • : N-acyl-aliphatic-L-amino acid amidohydrolase • : aspartoacylase • : acetylornithine deacetylase • : acyl-lysine deacylase • : succinyl-diaminopimelate desuccinylase • : nicotinamidase • : citrullinase • : N-acetyl-β-alanine deacetylas • : pantothenase • : ceramidase • : choloylglycine hydrolase • : N-acetylglucosamine-6-phosphate deacetylase • : N4-(β-N-acetylglucosaminyl)-L-asparaginase • EC 3.5.1.27: The activity is covered by , peptide deformylase • : N-acetylmuramoyl-L-alanine amidase • : 2-(acetamidomethylene)succinate hydrolase • : 5-aminopentanamidase • : formylmethionine deformylase • : hippurate hydrolase • : N-acetylglucosamine deacetylase • EC 3.5.1.34: 3.4.13.5)), Xaa-methyl-His dipeptidase|Identical with , Xaa-methyl-His dipeptidase • : D-glutaminase • : N-methyl-2-oxoglutaramate hydrolase • EC 3.5.1.37: 3.5.1.26)) N(4)-(β-N-acetylglucosaminyl)-L-asparaginase|Delete, identical with N4-(β-N-acetylglucosaminyl)-L-asparaginase • : glutamin-(asparagin-)ase • : alkylamidase • : acylagmatine amidase • : chitin deacetylase • : nicotinamide-nucleotide amidase • : peptidyl-glutaminase • : protein-glutamine glutaminase • EC 3.5.1.45: Now listed only as urea carboxylase • : 6-aminohexanoate-dimer hydrolase • : N-acetyldiaminopimelate deacetylase • : acetylspermidine deacetylase • : formamidase • : pentanamidase • : 4-acetamidobutyryl-CoA deacetylase • : peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase • : N-carbamoylputrescine amidase • : allophanate hydrolase • : long-chain-fatty-acyl-glutamate deacylase • : N,N-dimethylformamidase • : tryptophanamidase • : N-benzyloxycarbonylglycine hydrolase • : N-carbamoylsarcosine amidase • : N-(long-chain-acyl)ethanolamine deacylase • : mimosinase • : acetylputrescine deacetylase • : 4-acetamidobutyrate deacetylase • : Nα-benzyloxycarbonylleucine hydrolase • : theanine hydrolase • : 2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase • : 4-methyleneglutaminase • : N-formylglutamate deformylase • : glycosphingolipid deacylase • : aculeacin-A deacylase • : N-feruloylglycine deacylase • : D-benzoylarginine-4-nitroanilide amidase • : carnitinamidase • : chenodeoxycholoyltaurine hydrolase • : urethanase • : arylalkyl acylamidase • : N-carbamoyl-D-amino-acid hydrolase • : glutathionylspermidine amidase • : phthalyl amidase • EC 3.5.1.80: Identical to , N-acetylglucosamine-6-phosphate deacetylase • : N-acyl-D-amino-acid deacylase • : N-acyl-D-glutamate deacylase • : N-acyl-D-aspartate deacylase • : biuret amidohydrolase • : (S)-N-acetyl-1-phenylethylamine hydrolase • : mandelamide amidase • : N-carbamoyl-L-amino-acid hydrolase • : peptide deformylase • : N-acetylglucosaminylphosphatidylinositol deacetylase • : adenosylcobinamide hydrolase • : N-substituted formamide deformylase • : pantetheine hydrolase • : glutaryl-7-aminocephalosporanic-acid acylase • : γ-glutamyl-γ-aminobutyrate hydrolase • : N-malonylurea hydrolase • : succinylglutamate desuccinylase • : acyl-homoserine-lactone acylase • : histone deacetylase • : fatty acid amide hydrolase • : (R)-amidase • : L-proline amide hydrolase • : 2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5′-monophosphate deformylase • : N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-α-D-glucopyranoside deacetylase • : peptidoglycan-N-acetylglucosamine deacetylase • : chitin disaccharide deacetylase • : N-formylmaleamate deformylase • : maleamate amidohydrolase • : UDP-3-O-acyl-N-acetylglucosamine deacetylase • : sphingomyelin deacylase • : ureidoacrylate amidohydrolase • : 2-oxoglutaramate amidase • : 2′-N-acetylparomamine deacetylase • : 2′′′-acetyl-6′′′-hydroxyneomycin C deacetylase • : N-acyl-aromatic-L-amino acid amidohydrolase • : mycothiol S-conjugate amidase • : ureidoglycolate amidohydrolase • : 6-aminohexanoate-oligomer endohydrolase • : γ-glutamyl hercynylcysteine S-oxide hydrolase • : Pup amidohydrolase • EC 3.5.1.120: Now , 2-aminomuconate deaminase (2-hydroxymuconate-forming) • : protein N-terminal asparagine amidohydrolase • : protein N-terminal glutamine amidohydrolase • : γ-glutamylanilide hydrolase • : protein deglycase • : N 2-acetyl-L-2,4-diaminobutanoate deacetylase • : oxamate amidohydrolase • : jasmonoyl-L-amino acid hydrolase • : deaminated glutathione amidase • : N 5-(cytidine 5′-diphosphoramidyl)-L-glutamine hydrolase • : (amino group carrier protein)-lysine hydrolase|[amino group carrier protein]-lysine hydrolase • : 1-carboxybiuret hydrolase • : (amino group carrier protein)-ornithine hydrolase|[amino group carrier protein]-ornithine hydrolase • : N α-acyl-L-glutamine aminoacylase • : (indol-3-yl)acetyl-L-aspartate hydrolase • : N 4-acetylcytidine amidohydrolase • : N,N′-diacetylchitobiose non-reducing end deacetylase 3.5.2: In cyclic amides • : barbiturase • : dihydropyrimidinase • : dihydroorotase • : carboxymethylhydantoinase • : allantoinase • : β-lactamase • : imidazolonepropionase • EC 3.5.2.8: Now included with , β-lactamase • : 5-oxoprolinase (ATP-hydrolysing) • : creatininase • : L-lysine-lactamase • : 6-aminohexanoate-cyclic-dimer hydrolase • : 2,5-dioxopiperazine hydrolase • : N-methylhydantoinase (ATP-hydrolysing) • : cyanuric acid amidohydrolase • : maleimide hydrolase • : hydroxyisourate hydrolase • : enamidase • : streptothricin hydrolase • : isatin hydrolase 3.5.3: In linear amidines • : arginase • : guanidinoacetase • : creatinase • : allantoicase • : formimidoylaspartate deiminase • : arginine deiminase • : guanidinobutyrase • : formimidoylglutamase • : allantoate deiminase • : D-arginase • : agmatinase • : agmatine deiminase • : formimidoylglutamate deiminase • : amidinoaspartase • : protein-arginine deiminase • : methylguanidinase • : guanidinopropionase • : dimethylargininase • EC 3.5.3.19: Now , ureidoglycolate amidohydrolase • : diguanidinobutanase • : Methylenediurea deaminase • : proclavaminate amidinohydrolase • : N-succinylarginine dihydrolase • : N 1-aminopropylagmatine ureohydrolase • : N ω-hydroxy-L-arginine amidinohydrolase • : (S)-ureidoglycine aminohydrolase 3.5.4: In cyclic amidines • : cytosine deaminase • : adenine deaminase • : guanine deaminase • : adenosine deaminase • : cytidine deaminase • : AMP deaminase • : ADP deaminase • : aminoimidazolase • : methenyltetrahydrofolate cyclohydrolase • : IMP cyclohydrolase • : pterin deaminase • : dCMP deaminase • : dCTP deaminase • EC 3.5.4.14: Now included in , (deoxy)cytidine deaminase • : guanosine deaminase • : GTP cyclohydrolase I • : adenosine-phosphate deaminase • : ATP deaminase • : phosphoribosyl-AMP cyclohydrolase • : pyrithiamine deaminase • : creatinine deaminase • : 1-pyrroline-4-hydroxy-2-carboxylate deaminase • : blasticidin-S deaminase • : sepiapterin deaminase • : GTP cyclohydrolase II • : diaminohydroxyphosphoribosylaminopyrimidine deaminase • : methenyltetrahydromethanopterin cyclohydrolase • : S-adenosylhomocysteine deaminase • : GTP cyclohydrolase IIa • : dCTP deaminase (dUMP-forming) • : S-methyl-5′-thioadenosine deaminase • : 8-oxoguanine deaminase • : tRNA(adenine34) deaminase • : tRNAAla(adenine37) deaminase • : tRNA(cytosine8) deaminase • : mRNA(cytosine6666) deaminase • : double-stranded RNA adenine deaminase • : single-stranded DNA cytosine deaminase • : GTP cyclohydrolase IV • : aminodeoxyfutalosine deaminase • : 5'-deoxyadenosine deaminase • : N-isopropylammelide isopropylaminohydrolase • : hydroxydechloroatrazine ethylaminohydrolase • : ectoine hydrolase • : melamine deaminase • : cAMP deaminase 3.5.5: In nitriles • : nitrilase • : ricinine nitrilase • EC 3.5.5.3: Now , cyanate hydratase • : cyanoalanine nitrilase • : arylacetonitrilase • : bromoxynil nitrilase • : aliphatic nitrilase • : thiocyanate hydrolase 3.5.99: In other compounds • : riboflavinase • : aminopyrimidine aminohydrolase • EC 3.5.99.3: Now , hydroxydechloroatrazine ethylaminohydrolase • EC 3.5.99.4: Now , N-isopropylammelide isopropylaminohydrolase • : 2-aminomuconate deaminase • : glucosamine-6-phosphate deaminase • : 1-aminocyclopropane-1-carboxylate deaminase • : 5-nitroanthranilic acid aminohydrolase • : 2-nitroimidazole nitrohydrolase • : 2-iminobutanoate/2-iminopropanoate deaminase • : 2-aminomuconate deaminase (2-hydroxymuconate-forming) • : (S)-norcoclaurine synthase ==EC 3.6: Acting on acid anhydrides==

3.6.1: In phosphorus-containing anhydrides • : inorganic diphosphatase • : trimetaphosphatase • : adenosinetriphosphatase • EC 3.6.1.4: Now included with , adenosinetriphosphatase • : apyrase • : nucleoside diphosphate phosphatase • : acylphosphatase • : ATP diphosphatase • : nucleotide diphosphatase • : endopolyphosphatase • : exopolyphosphatase • : dCTP diphosphatase • : ADP-ribose diphosphatase • : adenosine-tetraphosphatase • : nucleoside-triphosphatase • : CDP-glycerol diphosphatase • : bis(5′-nucleosyl)-tetraphosphatase (asymmetrical)) • : FAD diphosphatase • EC 3.6.1.19: Now , nucleotide diphosphatase • : 5′-acylphosphoadenosine hydrolase • : ADP-sugar diphosphatase • : NAD+ diphosphatase • : dUTP diphosphatase • : nucleoside phosphoacylhydrolase • : triphosphatase • : CDP-diacylglycerol diphosphatase • : undecaprenyl-diphosphatase • : thiamine-triphosphatase • : bis(5′-adenosyl)-triphosphatase • EC 3.6.1.30: Now covered by [m7GpppX diphosphatase] and [m7GpppN-mRNA hydrolase]. • : phosphoribosyl-ATP diphosphatase • EC 3.6.1.32: Now , myosin ATPase • EC 3.6.1.33: Now , dynein ATPase • EC 3.6.1.34: Transferred entry: H+-transporting ATP synthase. Now , H+-transporting two-sector ATPase • EC 3.6.1.35: Now , H+-exporting ATPase • EC 3.6.1.36: Now , H+/K+-exchanging ATPase • EC 3.6.1.37: Now , Na+/K+-exchanging ATPase • EC 3.6.1.38: Now , Ca2+-transporting ATPase • : thymidine-triphosphatase • : guanosine-5′-triphosphate,3′-diphosphate phosphatase • : bis(5′-nucleosyl)-tetraphosphatase (symmetrical) • : guanosine-diphosphatase • : dolichyldiphosphatase • : oligosaccharide-diphosphodolichol diphosphatase • : UDP-sugar diphosphatase • EC 3.6.1.46: Now , heterotrimeric G-protein GTPase • EC 3.6.1.47: Now , protein-synthesizing GTPase • EC 3.6.1.49: Now , signal-recognition-particle GTPase • EC 3.6.1.50: Now , dynamin GTPase • EC 3.6.1.51: Now , tubulin GTPase • : diphosphoinositol-polyphosphate diphosphatase • : Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase • : UDP-2,3-diacylglucosamine diphosphatase • : 8-oxo-dGTP diphosphatase • : 2-hydroxy-dATP diphosphatase • : UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase • : 8-oxo-dGDP phosphatase • : m7GpppX diphosphatase|5′-(N7-methyl 5′-triphosphoguanosine)-[mRNA] diphosphatase • : diadenosine hexaphosphate hydrolase (AMP-forming) • : diadenosine hexaphosphate hydrolase (ATP-forming) • : m7GpppN-mRNA hydrolase|5′-(N7-methylguanosine 5′-triphospho)-[mRNA] hydrolase • : α-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase • : inosine diphosphate phosphatase • : (d)CTP diphosphatase • : XTP/dITP diphosphatase • : dihydroneopterin triphosphate diphosphatase • : geranyl diphosphate phosphohydrolase • : 8-oxo-(d)GTP phosphatase • : guanosine-5′-diphospho-5′-(DNA) diphosphatase|guanosine-5′-diphospho-5′-[DNA] diphosphatase • : adenosine-5′-diphospho-5′-(DNA) diphosphatase|adenosine-5′-diphospho-5′-[DNA] diphosphatase • : DNA-3′-diphospho-5′-guanosine diphosphatase • : inosine/xanthosine triphosphatase • : mRNA 5′-phosphatase 3.6.2: In sulfonyl-containing anhydrides • : adenylylsulfatase • : phosphoadenylylsulfatase 3.6.3: Acting on acid anhydrides to catalyse transmembrane movement of substances • : phospholipid-translocating ATPase • EC 3.6.3.2: Now , P-type Mg2+ transporter • EC 3.6.3.3: Now , Cd2+-exporting ATPase • EC 3.6.3.4: Now , Cu2+-exporting ATPase • EC 3.6.3.5: Now , Zn2+-exporting ATPase • EC 3.6.3.6: Now , P-type H+-exporting transporter • EC 3.6.3.7: Now , P-type Na+ transporter • EC 3.6.3.8: Now , Ca2+-transporting ATPase • EC 3.6.3.9: Now , Na+/K+-exchanging ATPase • EC 3.6.3.10: Now , H+/K+-exchanging ATPase • EC 3.6.3.11: "Cl–-transporting ATPase". The activity was only ever studied in crude extracts, and is an artifact • EC 3.6.3.12: Now , K+-transporting ATPase • EC 3.6.3.13:Identical to , phospholipid-translocating ATPase • EC 3.6.3.14: Now , H+-transporting two-sector ATPase • EC 3.6.3.15: Now , Na+-transporting two-sector ATPase • EC 3.6.3.16: Now , arsenite-transporting ATPase • EC 3.6.3.17: Now covered by various ABC-type monosaccharide transporters in sub-subclass EC 7.5.2 • EC 3.6.3.18: Now , ABC-type oligosaccharide transporter • EC 3.6.3.19: Now , ABC-type maltose transporter • EC 3.6.3.20: Now , glycerol-3-phosphate-transporting ATPase • EC 3.6.3.21: Now , ABC-type polar-amino-acid transporter • EC 3.6.3.22: Now , ABC-type nonpolar-amino-acid transporter • EC 3.6.3.23: Now , oligopeptide-transporting ATPase • EC 3.6.3.24: Now , nickel-transporting ATPase • EC 3.6.3.25: Now , sulfate-transporting ATPase • EC 3.6.3.26: Now , nitrate-transporting ATPase • EC 3.6.3.27: Now , ABC-type phosphate transporter • EC 3.6.3.28: Now , ABC-type phosphonate transporter • EC 3.6.3.29: Now , molybdate-transporting ATPase • EC 3.6.3.30: Now , Fe3+-transporting ATPase • EC 3.6.3.31: Now , polyamine-transporting ATPase • EC 3.6.3.32: Now , quaternary-amine-transporting ATPase • EC 3.6.3.33: Now , vitamin B12-transporting ATPase • EC 3.6.3.34: now recognized to be at least three separate enzymes , iron(III) hydroxamate ABC transporter, , ferric enterobactin ABC transporter, and , ferric citrate ABC transporter • EC 3.6.3.35: Now , manganese-transporting ATPase • EC 3.6.3.36: Now , taurine-transporting ATPase • EC 3.6.3.37: Now , guanine-transporting ATPase • EC 3.6.3.38: Now , ABC-type capsular-polysaccharide transporter • EC 3.6.3.39: Now , lipopolysaccharide-transporting ATPase • EC 3.6.3.40: Now , teichoic-acid-transporting ATPase • EC 3.6.3.41: Now , heme-transporting ATPase • EC 3.6.3.42: Now , β-glucan-transporting ATPase • EC 3.6.3.43: Now , peptide-transporting ATPase • EC 3.6.3.44: Now , ABC-type xenobiotic transporter • EC 3.6.3.45: Now included with , xenobiotic-transporting ATPase • EC 3.6.3.46: Now , ABC-type Cd2+ transporter • EC 3.6.3.47: Now , fatty-acyl-CoA-transporting ATPase • EC 3.6.3.48: Now as α-factor-pheromone transporting ATPase • EC 3.6.3.49: Now , channel-conductance-controlling ATPase • EC 3.6.3.50: Now , protein-secreting ATPase • EC 3.6.3.51: Now , mitochondrial protein-transporting ATPase • EC 3.6.3.52: Now , chloroplast protein-transporting ATPase • EC 3.6.3.53: Now , Ag+-exporting ATPase • EC 3.6.3.54: Now , Cu+-exporting ATPase • EC 3.6.3.55: Now , tungstate-importing ATPase 3.6.4: Acting on acid anhydrides to facilitate cellular and subcellular movement • EC 3.6.4.1: Now , myosin ATPase • EC 3.6.4.2: Now , dynein ATPase • EC 3.6.4.3: Now , microtubule-severing ATPase • EC 3.6.4.4: Now , plus-end-directed kinesin ATPase • EC 3.6.4.5: Now , minus-end-directed kinesin ATPase • : vesicle-fusing ATPase • : peroxisome-assembly ATPase • EC 3.6.4.8: Now , proteasome ATPase • EC 3.6.4.9: Now , chaperonin ATPase • : non-chaperonin molecular chaperone ATPase • EC 3.6.4.11: Deleted, the activity has been shown not to take place • : DNA helicase • : RNA helicase 3.6.5: Acting on GTP to facilitate cellular and subcellular movement • : heterotrimeric G-protein GTPase • : small monomeric GTPase • : protein-synthesizing GTPase • : signal-recognition-particle GTPase • : dynamin GTPase • : tubulin GTPase ==EC 3.7: Acting on carbon-carbon bonds==

EC 3.7.1: In ketonic substances • : oxaloacetase • : fumarylacetoacetase • : kynureninase • : phloretin hydrolase • : acylpyruvate hydrolase • : acetylpyruvate hydrolase • : β-diketone hydrolase • : 2,6-dioxo-6-phenylhexa-3-enoate hydrolase • : 2-hydroxymuconate-semialdehyde hydrolase • : cyclohexane-1,3-dione hydrolase • : cyclohexane-1,2-dione hydrolase • : cobalt-precorrin 5A hydrolase • : 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase • : 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase • EC 3.7.1.15: Now , (+)-caryolan-1-ol synthase • EC 3.7.1.16: Now , oxepin-CoA hydrolase • : 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase • : 6-oxocamphor hydrolase • : 2,6-dihydroxypseudooxynicotine hydrolase • : 3-fumarylpyruvate hydrolase • : 6-oxocyclohex-1-ene-1-carbonyl-CoA hydratase • : 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (ring-opening) • : maleylpyruvate hydrolase • : 2,4-diacetylphloroglucinol hydrolase • : 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase • : 2,4-didehydro-3-deoxy-L-rhamnonate hydrolase • : neryl diphosphate diphosphatase • : 3-oxoisoapionate-4-phosphate transcarboxylase/hydrolase ==EC 3.8: Acting on halide bonds==

===EC 3.8.1: Acting on halide bonds=== • EC 3.8.1.1: Covered by , haloalkane dehalogenase. • : (S)-2-haloacid dehalogenase • : haloacetate dehalogenase • EC 3.8.1.4: Now , thyroxine 5′-deiodinase • : haloalkane dehalogenase • : 4-chlorobenzoate dehalogenase • : 4-chlorobenzoyl-CoA dehalogenase • : atrazine chlorohydrolase • : (R)-2-haloacid dehalogenase • : 2-haloacid dehalogenase (configuration-inverting) • : 2-haloacid dehalogenase (configuration-retaining) 3.8.2: In phosphorus-halide compounds (deleted sub-subclass) • EC 3.8.2.1: Now , diisopropyl-fluorophosphatase ==EC 3.9: act on phosphorus-nitrogen bonds==

EC 3.9.1: Acting on phosphorus-nitrogen bonds (only sub-subclass identified to date) • : phosphoamidase • : protein arginine phosphatase • : phosphohistidine phosphatase ==EC 3.10: Acting on sulfur-nitrogen bonds==

EC 3.10.1: Acting on sulfur-nitrogen bonds (only sub-subclass identified to date) • : N-sulfoglucosamine sulfohydrolase • : cyclamate sulfohydrolase ==EC 3.11: Acting on carbon-phosphorus bonds==

EC 3.11.1: Acting on carbon-phosphorus bonds (only sub-subclass identified to date) • : phosphonoacetaldehyde hydrolase • : phosphonoacetate hydrolase • : phosphonopyruvate hydrolase ==EC 3.12: Acting on sulfur-sulfur bonds==

EC 3.12.1: Acting on sulfur-sulfur bonds (only sub-subclass identified to date) • : trithionate hydrolase ==EC 3.13: Acting on carbon-sulfur bonds==

EC 3.13.1: Acting on carbon-sulfur bonds (only sub-subclass identified to date) • : UDP-sulfoquinovose synthase • EC 3.13.1.2: Deleted, the activity is most probably attributable to , S-ribosylhomocysteine lyase • : 2′-hydroxybiphenyl-2-sulfinate desulfinase • : 3-sulfinopropanoyl-CoA desulfinase • : carbon disulfide hydrolase • : (CysO sulfur-carrier protein)-S-L-cysteine hydrolase|[CysO sulfur-carrier protein]-S-L-cysteine hydrolase • : Carbonyl sulfide hydrolase • : S-adenosyl-L-methionine hydrolase (adenosine-forming) • : S-inosyl-L-homocysteine hydrolase ==References==