•
Jonathan Safran Foer (born 1977) – novelist •
Carl Sagan (1934–1996) – scientist, author, educator (
Bensonhurst) •
Saigon (born 1977) – actor and rapper •
Stephanie Saland – ballet dancer and teacher •
Claudia Peña Salinas (born 1975) – artist •
Dmitri Salita (born 1982) – boxer •
William Salter (1821–1910) – minister, public orator, social activist, and historian •
Arnold A. Saltzman (1916–2014) – businessman, diplomat, art collector, and philanthropist •
John Samuelsen – labor union leader •
Julia Sand (1848–1933) – letter writer who corresponded with President
Chester A. Arthur •
Bernie Sanders (born 1941) –
Independent U.S. senator from
Vermont (
Madison) •
Jane Sanders (born 1950) – social worker, college administrator, activist, and political strategist •
Adam Sandler (born 1966) – actor and comedian •
Evie Sands (born 1946) – singer-songwriter and musician •
Betty Santoro (1938–2005) – educator, activist and community leader •
Porter Sargent (1872–1951) – educational theorist and critic •
Peter Sarsgaard (born 1971) – actor •
Lois Sasson (1940–2020) – jewelry designer and gay rights activist •
Brittney Savage (born 1987) – professional wrestler •
Viola Savoy (1899–1987) – actress •
Leo Schachter (1924–2019) – diamond manufacturer •
Roger Schank (born 1946) –
education reformer,
artificial-intelligence expert •
Kenny Scharf (born 1958) – graffiti artist •
Ossie Schectman (1919–2013) – NBA basketball guard •
Robert Scherrer (1935–1995) – FBI agent •
Thomas D. Schiano (born 1962) –
organ-transplantation specialist •
Vincent Schiavelli (1948–2005) − actor, food writer •
Phil Schiliro (born 1956) – political consultant and strategist •
Justin G. Schiller (born 1943) – bookseller •
Vincent Schiraldi (born 1959) – juvenile justice policy reformer and activist •
Steve Schirripa (born 1957) – actor (
Bensonhurst) •
Harvey Schlossberg (1936–2021) – psychoanalyst, police officer, and founder of modern crisis negotiation •
Michael Schlow – chef and restaurateur •
Ruth A. M. Schmidt (1916–2014) – geologist and paleontologist •
Tobias Schneebaum (1922–2005) – artist, anthropologist, and AIDS activist •
Robert Scholes (1929–2016) – literary critic and theorist •
Andre-Michel Schub (born 1952) – pianist (
Midwood) •
Peter C. Schultz (born 1942) – co-inventor of
fiber optics •
Chuck Schumer (born 1950) –
U.S. senator from New York (
Flatbush) •
Alan Schwartz – businessman; executive chairman of
Guggenheim Partners •
Gary Schwartz (born 1940) – art historian •
Ylon Schwartz – chessmaster •
Joseph E. Schwartzberg (1928–2018) – writer, academic, and peace activist •
Seymour Schwartzman (1930–2009) – opera singer and
cantor •
Chris Matthew Sciabarra (born 1960) – political theorist •
Brian Scolaro (born 1973) – comedian, actor, voice-over actor and author •
Raymond Scott (born Harry Warnow, 1908–1994) – composer, bandleader, pianist,
electronic-music pioneer •
Samuel R. Scottron (1841–1905) – inventor and engineer •
John Scully (1846–1917) – Jesuit priest and president of
Fordham University •
Neil Sedaka (1939–2026) – singer-songwriter •
Alice Wiley Seay (1858–1937) – social worker and founder of the
Empire State Federation of Women's Clubs •
Alonzo Bertram See (1849–1941) – businessman •
Murray Seeman (1914–2017) – lawyer and real estate developer •
Erich Segal (1937–2010) – author,
Academy Award-nominated screenwriter, and educator (
Midwood) •
Hugh Seidman (1940–2023) – poet •
Steven Seifert (1950–2022) – medical toxicologist •
Jerry Seinfeld (born 1954) – actor and comedian (
Borough Park) •
Matt Zoller Seitz (born 1968) – film and television critic, author and filmmaker •
Hubert Selby, Jr. (1928–2004) – author •
Cletus Seldin (born 1986) – boxer •
Phil Sellers (born 1953) – former NBA player •
Irene Mayer Selznick (1907–1990) – socialite and theatrical producer •
George I. Seney (1826–1893) – banker, art collector, and philanthropist •
Greg Serano (born 1974) – actor •
Frank Serpico (born 1936) – New York Police Department detective and whistleblower •
John Severin (1921–2012) – comics artist •
Marie Severin (1929–2018) – comics artist and colorist •
Shabazz the Disciple (born 1973) – rapper (
Red Hook) •
William Shadish (1949–2016) – psychologist and statistician •
Ruth Shafer (1912 –1972) – engineer •
Juliet Popper Shaffer (born 1932) – psychologist and statistician •
Neal Shapiro (born 1945) – equestrian and Olympic medalist •
Judy Shapiro-Ikenberry (born 1942) – long-distance runner •
Francis Ethelbert Sharkey – fictional character played by Terry Becker in the 1964–68
ABC television series
Voyage to the Bottom of the Sea •
Judith Sheindlin (born 1942) – television personality,
Judge Judy (
Madison /
Bedford–Stuyvesant) •
Lawrence L. Shenfield (1891–1974) – advertising executive •
Allie Sherman (1923–2015) – NFL player and coach •
Art Sherman (born 1937) – horse trainer and jockey •
Fred Sherman (1924–2009) – economist and business commentator •
Jerome K. Sherman (1925–2023) – biologist and founder of modern sperm banking and cryopreservation •
Bobby Shmurda (born 1994) – rapper from GS9 (East Flatbush) •
Lester Shorr (1907–1992) – cinematographer •
Marjorie Shostak (1945–1996) – anthropologist •
Michael Showalter (born 1970) – actor and comedian •
Shyne (born Jamal Michael Barrow; 1978), Belizean rapper and politician •
Gabourey Sidibe (born 1983) – actress (
Bedford–Stuyvesant) •
Bugsy Siegel (1906–1947) – gangster •
Jill Sigman – choreographer and dancer •
Raymond Siller (born 1939) – television writer,
political consultant •
Beverly Sills (1929–2007) – opera singer •
Dean Silvers – film director, film producer, screenwriter, and author (
East Flatbush) •
Phil Silvers (1911–1985) – actor and comedian •
John Sitaras (born 1972) – fitness professional •
David Sive (1922–2014) – attorney, environmentalist, and professor of environmental law •
Skoob – half of rap duo
Das EFX •
Justine Skye (born 1995) – singer-songwriter, dancer and model •
Harold S. Sloan (1888–1988) – economist •
Buzz Slutzky (born 1988) – artist, writer, educator, and performer •
Peer Smed (1878–1943) – silversmith •
Smif-n-Wessun – hip-hop duo •
Frank H. Smith – media executive and producer •
Lois Smith (1928–2012) – publicist •
Lucy Eaton Smith (1845–1894) – nun •
Munroe Smith (1854–1926) – jurist and historian •
Philip F. Smith (1932–2017) –
Master Chief Petty Officer of the Coast Guard •
Sanford L. Smith (1939–2024) – businessman •
Jimmy Smits (born 1955) – actor •
Stephen Edward Smith (1927–1990) – financial analyst and political strategist who was the husband of
Jean Kennedy Smith •
Pop Smoke (1999–2020) – rapper (Canarsie) •
Joel Smoller (1936–2017) – mathematician •
Culver C. Sniffen (1844–1930) –
Paymaster-General of the United States Army •
Ralph Snyderman (born 1940) – physician, scientist, administrator (
Bensonhurst) •
Robert Solow (1924–2023) – economist; winner of the
Nobel Memorial Prize in Economic Sciences (
Madison) •
Lee Solters (1919–2009) – press agent •
Gilbert Sorrentino (1929–2006) – novelist, short story writer, poet, literary critic, and editor •
Paul Sorvino (1939–2022) – actor •
Carl Søyland (1894–1978) – editor-in-chief of
Nordisk Tidende •
Paul Spatola – musician •
Mortimer Spiegelman (1901–1969) – statistician •
Michael Spiller (born 1961) – cinematographer and television director •
DJ Spinderella (born 1971) – DJ and rapper •
William F. Spurgin (1838–1904) – US Army brigadier general, lived in Brooklyn during retirement •
Lamuel A. Stanislaus (1921–2016) – dentist and diplomat •
Jessie Stanton (1887–1976) – writer •
Barbara Stanwyck (1907–1990) – Oscar-winning actress •
Adele Starr (1920–2010) – activist •
Peter Steele (1962–2010) – bassist and singer (
Type O Negative,
Carnivore) (
Midwood) •
Charles M. Stein (1920–2016) – statistician and academic •
Seymour Stein (1942–2023) – entrepreneur and music executive •
Norman Steinberg (1939–2023) – television director, producer and screenwriter •
Douglas C. Steiner (born 1960) – real estate developer •
Gilbert Y. Steiner (1924–2006) – scholar and president of the
Brookings Institution •
Charles Stendig (1924–2024) – businessman and philanthropist •
Gary Stephan (born 1942) – artist •
Lance Stephenson (born 1990) – basketball player •
Ray Stern (1933–2007) – professional wrestler, bodybuilder and entrepreneur •
Stuart Sternberg (born 1959) – owner of the
Tampa Bay Rays •
Connie Stevens (born 1938) – actress and singer •
Neil M. Stevenson (1930–2009) – chief of chaplains of the
U.S. Navy •
Bob Stewart (1920–2012) – television producer •
Sticky Fingaz (born 1973), born Kirk Jones, member of the rap group
Onyx •
Jerry Stiller (1927–2020) – actor, father of Ben Stiller •
Lulu G. Stillman (1881 or 1882–1969) – activist for Native American rights •
Frederick A. Stokes (1857–1939) – publisher •
David Stones (born 1988) – rapper •
Ruth Storey (1913–1997) – actress •
Jeff Strabone – scholar, political activist and civic leader •
Granville Straker (born 1939) – music businessman and record producer •
Evelyn Straus (1916–1992) – photojournalist •
Barbra Streisand (born 1942) – Oscar-winning actress, singer, director, political activist (
Williamsburg) •
Jason Sudeikis (born 1975) – actor and comedian (Clinton Hill) •
Daniel Suhr (1964–2001) – first firefighter to die in the
September 11 attacks •
Jackie Summers – microdistiller, writer and chief executive officer of Jack from Brooklyn •
Laura Sumner (1921–1993) – numismatist and poet •
Rowena Swanson (born 1928) – information scientist •
Glenn Switkes (1951–2009) – environmentalist and film-maker •
Richard Sylbert (1928–2002) – film production designer and art director •
Harold Syrett (1913–1984) – president of
Brooklyn College == T ==