•
Hydrolytic enzyme ===
:Category:EC 3.1 (act on
ester bonds)=== •
Nuclease •
Endonuclease •
Exonuclease •
:Category:EC 3.1.1 •
Acid hydrolase •
Phospholipase A () •
Acetylcholinesterase () •
Cholinesterase () •
Lipoprotein lipase () •
:Category:EC 3.1.2 •
Ubiquitin carboxy-terminal hydrolase L1 () •
:Category:EC 3.1.3 •
Phosphatase •
Alkaline phosphatase () •
Fructose bisphosphatase () •
:Category:EC 3.1.4 •
Phospholipase C () •
CGMP specific phosphodiesterase type 5 () •
Phospholipase D () •
:Category:EC 3.1.21 •
Restriction enzyme Type 1 () •
Restriction enzyme Type 2 () •
Restriction enzyme Type 3 () •
Restriction enzyme Type 4 (?) •
Deoxyribonuclease I () •
:Category:EC 3.1.26 •
RNase H () •
:Category:EC 3.1.27 •
Ribonuclease ===
:Category:EC 3.2 (act on sugars -
glycosylases)=== •
:Category:EC 3.2.1 •
Amylase () •
Sucrase () •
Chitinase () •
Lysozyme () •
Maltase () •
Lactase () •
Beta-galactosidase () •
Hyaluronidase ()
Function and clinical importance of some enzymes in category 3.2.1 Amylase Function: Amylase is an enzyme that is responsible for the breaking of the bonds in starches, polysaccharides, and complex carbohydrates to be turned into simple sugars that will be easier to absorb.
Clinical Significance: Amylase also has medical history in the use of Pancreatic Enzyme Replacement Therapy (PERT). One of the components is Sollpura (liprotamase), which help in the breakdown of saccharides into simple sugars.
Lysozyme Function: An enzyme that is produced by animals that forms part of the innate immune system and is abundant in the secretions of saliva, human milk, tears, and mucus. It functions as an antimicrobial agent by splitting the peptidoglycan component of bacterial cell walls, which then leads to cell death.
Clinical Significance: Toxic levels of blood are caused by the excessive production of lysozyme's by cancer cells. Lysozyme's have also been associated with Bronchopulmonary dysplasia (BPD) in newborns and is a key factor in providing the immunology of infants during breast feeding.
Sucrase Function: Sucrase is a stomachs related protein that mobilizes hydrolysis to convert sucrose into glucose and fructose.
Clinical Significance: Low amounts of Sucrose also known as
Sucrose intolerance happens when sucrose isn't being discharged in the small digestive tract. A result of this is extra gas.
Lactase Function: lactase is located in the small digestives system of people and other creatures such as
mammals. Lactase is the bases of the total absorption of milk.
Clinical Significance: People who are lactose intolerant have medicine that can help with the digestion. When you are lactose intolerant you might experience gas, bloating, and pain along with other symptoms regarding your digestive system. ===
:Category:EC 3.3 (act on
ether bonds)=== •
:Category:EC 3.3 •
Adenosylmethionine hydrolase •
S-adenosyl-L-homocysteine hydrolase •
Alkenylglycerophosphocholine hydrolase •
Alkenylglycerophosphoethanolamine hydrolase •
Cholesterol-5,6-oxide hydrolase •
Hepoxilin-epoxide hydrolase •
Isochorismatase •
Leukotriene-A4 hydrolase •
Limonene-1,2-epoxide hydrolase •
Microsomal epoxide hydrolase •
Trans-epoxysuccinate hydrolase ===
:Category:EC 3.4 (act on
peptide bonds -
Peptidase)=== •
:Category:EC 3.4.11 •
Alanine aminopeptidase •
:Category:EC 3.4.15 •
Angiotensin converting enzyme •
:Category:EC 3.4.21 •
Serine protease •
Chymotrypsin () •
Trypsin () •
Thrombin () •
Factor X () •
Plasmin () •
Acrosin () •
Factor VII () •
Factor IX () •
Prolyl oligopeptidase () •
Factor XI () •
Elastase () •
Factor XII () •
Proteinase K () •
Tissue plasminogen activator () •
Protein C () •
:Category:EC 3.4.22 •
Separase () •
:Category:EC 3.4.23 •
Pepsin () •
Rennet () •
Renin () •
Trypsinogen () and (20/21/23/24/26) •
Plasmepsin () •
:Category:EC 3.4.24 •
Matrix metalloproteinase () •
:Category:EC 3.4.25 •
Metalloendopeptidase ===
:Category:EC 3.5 (act on carbon–nitrogen bonds, other than peptide bonds)=== •
:Category:EC 3.5.1 (In linear amides) •
Urease () •
:Category:EC 3.5.2 (In cyclic amides) •
Beta-lactamase () •
:Category:EC 3.5.3 (In linear amidines) •
Arginase () •
:Category:EC 3.5.4 (In cyclic amidines) •
Adenosine deaminase () •
GTP cyclohydrolase I () •
:Category:EC 3.5.5 (In nitriles) •
Nitrilase () ===
:Category:EC 3.6 (act on
acid anhydrides)=== •
:Category:EC 3.6.1 •
Helicase •
DnaB helicase •
RecQ helicase •
:Category:EC 3.6.3 •
ATPase •
NaKATPase () •
ATP synthase () ===
:Category:EC 3.7 (act on carbon–carbon bonds)=== •
Kynureninase ===
:Category:EC 3.8 (act on
halide bonds)=== • EC 3.8.1.3
Haloacetate dehalogenase ===
:Category:EC 3.9 (act on phosphorus–nitrogen bonds)=== • :
Phosphoamidase • :
Protein arginine phosphatase • : Phosphohistidine phosphatase ===
:Category:EC 3.10 (act on sulfur–nitrogen bonds)=== • :
N-sulfoglucosamine sulfohydrolase • :
Cyclamate sulfohydrolase ===
:Category:EC 3.11 (act on carbon–phosphorus bonds)=== • :
Phosphonoacetaldehyde hydrolase • :
Phosphonoacetate hydrolase • :
Phosphonopyruvate hydrolase ===
:Category:EC 3.12 (act on sulfur–sulfur bonds)=== • :
Trithionate hydrolase ===
:Category:EC 3.13 (act on carbon–sulfur bonds)=== • :
UDP-sulfoquinovose synthase • :
2'-hydroxybiphenyl-2-sulfinate desulfinase • : 3-sulfinopropanoyl—CoA desulfinase • :
Carbon disulfide hydrolase • : (CysO sulfur-carrier protein)-S-L-cysteine hydrolase • :
Carbonyl sulfide hydrolase • : S-adenosyl-L-methionine hydrolase (adenosine-forming) ==
:Category:Lyases (EC 4) (
Lyase)==